357278-41-2

Upstream product

• 100-46-9 benzylamine 
• 357278-39-8 (4R,5S)-3-benzyl-5-((1S)-2-tert-butyldiphenylsilyloxy-1-hydroxyethyl)-4-vinyl-1,3-oxazolan-2-one 
• 357278-33-2 Benzyl-{(R)-1-[(2R,3S)-3-(tert-butyl-diphenyl-silanyloxymethyl)-oxiranyl]-allyl}-amine 
• 357278-40-1 (4R,5S)-3-benzyl-5-((1S)-2-tert-butyldiphenylsilyloxy-1-benzyloxyethyl)-4-vinyl-1,3-oxazolan-2-one 

Downstream Products

• 949490-41-9 (4R,5S)-3-benzyl-5-((1S)-2-O-carbamoyl-1-benzyloxyethyl)-4-vinyl-1,3-oxazolan-2-one 
• 357278-45-6 (2R,3S,4S)-1-Benzyl-4-benzyloxy-2-vinyl-pyrrolidin-3-ol 
• 129077-29-8 (S)-1-((2R,3S,4S)-1-Benzyl-3,4-bis-benzyloxy-pyrrolidin-2-yl)-ethane-1,2-diol 
• 129077-19-6 (2R,3S,4S)-1-Benzyl-3,4-bis-benzyloxy-2-vinyl-pyrrolidine 
• 357278-43-4 (2S,3S,4R)-4-Benzylamino-2-benzyloxy-hex-5-ene-1,3-diol 

Relevant academic research and scientific papers

New approach to carbamoyl-polyoxamic acid derivatives through an oxazolidinone synthon

A key oxazolidinone synthon was obtained through condensation of vinyl magnesium with an epoxyimine, followed by a carbonation/cyclisation reaction in the presence of ammonium carbonate. Oxidative ozonolysis after protection and carbamolylation (optional)

A new access to polyhydroxylated pyrrolidines from epoxyaldehydes

Our approach relies on the stereocontrolled vinylation of a chiral α,β-epoxyimine derived from the corresponding aldehyde. Regioselective opening of the oxirane with carbonate anion allowed the formation of an oxazolidinone intermediate from which the glu