129077-29-8

Upstream product

• 129077-19-6 (2R,3S,4S)-1-Benzyl-3,4-bis-benzyloxy-2-vinyl-pyrrolidine 
• 129077-17-4 methyl 2,3-di-O-benzyl-6-bromo-6-deoxy-α-D-galactopyranoside 
• 100-39-0 benzyl bromide 
• 129077-18-5 (2S,3S,4S)-1-benzylamino-2,3-di-O-benzyl-hex-5-ene-2,3,4-triol 
• 29600-81-5 methyl 2,3-di-O-benzyl-4,6-O-benzylidene-α-D-galactopyranoside 
• 4288-93-1 methyl 4,6-O-benzylidene-α-D-galactopyranoside 
• 29388-46-3 methyl 2,3-di-O-benzyl-α-D-galactopyranoside 
• 357278-40-1 (4R,5S)-3-benzyl-5-((1S)-2-tert-butyldiphenylsilyloxy-1-benzyloxyethyl)-4-vinyl-1,3-oxazolan-2-one 
• 357278-39-8 (4R,5S)-3-benzyl-5-((1S)-2-tert-butyldiphenylsilyloxy-1-hydroxyethyl)-4-vinyl-1,3-oxazolan-2-one 
• 357278-33-2 Benzyl-{(R)-1-[(2R,3S)-3-(tert-butyl-diphenyl-silanyloxymethyl)-oxiranyl]-allyl}-amine 
• 357278-41-2 (4R,5S)-3-Benzyl-5-((S)-1-benzyloxy-2-hydroxy-ethyl)-4-vinyl-oxazolidin-2-one 
• 357278-43-4 (2S,3S,4R)-4-Benzylamino-2-benzyloxy-hex-5-ene-1,3-diol 
• 357278-45-6 (2R,3S,4S)-1-Benzyl-4-benzyloxy-2-vinyl-pyrrolidin-3-ol 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

A new access to polyhydroxylated pyrrolidines from epoxyaldehydes

Our approach relies on the stereocontrolled vinylation of a chiral α,β-epoxyimine derived from the corresponding aldehyde. Regioselective opening of the oxirane with carbonate anion allowed the formation of an oxazolidinone intermediate from which the glu

A SHORT, VERSATILE APPROACH TO POLYHYDROXYLATED PYRROLIDINES UTILIZING A REDUCTIVE ELIMINATION-REDUCTIVE AMINATION AS A KEY STEP

An efficient synthesis of epimeric alpha-vinyl pyrrolidines starting from methyl 4,6-O-benzyliden gluco- and galactopyranosides gave ready access to hydroxylated pyrrolidines.