35730-03-1

Basic information

• Product Name: 1-(4-chlorophenyl)-3-phenylpropan-2-one
• CAS NO: 35730-03-1
• Molecular Formula: C₁₅H₁₃ClO
• Molecular Weight: 244.7161
• Mol File: 35730-03-1.mol

Chemical Properties

• Boiling Point: 353.2°C at 760 mmHg
• Flash Point: 202.9°C
• Density: 1.173g/cm³
• Vapor Pressure: 3.65E-05mmHg at 25°C
• Refractive Index: 1.584
• CAS DataBase Reference: 1-(4-chlorophenyl)-3-phenylpropan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-3-phenylpropan-2-one(35730-03-1)
• EPA Substance Registry System: 1-(4-chlorophenyl)-3-phenylpropan-2-one(35730-03-1)

Safety Data

• Hazardous Substances Data: 35730-03-1(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical and Agrochemical Industries:
P4CP is utilized as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides. Its role in these industries is crucial for the production of a wide range of organic compounds.
Used in Perfumery and Fragrance Industry:
P4CP is employed as a key ingredient in the manufacture of perfumes and fragrances due to its strong and distinctive aroma. This application capitalizes on its sensory properties to create appealing scents for consumer products.
Used in Antimicrobial and Antifungal Applications:
In laboratory studies, P4CP has shown potential as an antimicrobial and antifungal agent. This suggests its use in the development of new treatments and preventive measures against microbial and fungal infections.
However, it is important to note that due to the potential health hazards associated with P4CP, it should be handled with care and proper safety measures to ensure the well-being of individuals involved in its production and use.

Upstream product

• 35741-47-0 2-(4-chlorophenyl)-3-oxo-4-phenyl-butanenitrile 
• 100-44-7 benzyl chloride 
• 25026-34-0 4-chlorophenacetyl chloride 
• 1878-66-6 4-chlorophenylacetic Acid 
• 103-82-2 phenylacetic acid 

Downstream Products

• 5216-35-3 1,2-bis(4-chlorophenyl)ethane 
• 14310-22-6 4-chlorobibenzyl 
• 103-29-7 1,1'-(1,2-ethanediyl)bisbenzene 
• 23923-18-4 4,5-Diphenyl-2,3-bis-(p-chlor-phenyl)-(αβ)-cyclopentadien-(2,4)-on-(1) 
• 24012-41-7 5-Phenyl-2,3,4-tris-(p-chlor-phenyl)-(αββ')-cyclopentadien-(2,4)-on-(1) 
• 38268-03-0 2-(4-chloro-phenyl)-3,4,5-triphenyl-cyclopentadienone 

Relevant articles and documents

Iron-Catalyzed One-Step Synthesis of Isothiazolone/1,2-Selenazolone Derivatives via [3+1+1] Annulation of Cyclopropenones, Anilines, and Elemental Chalcogens

Described herein is the one-step synthesis of isothiazolone/1,2-selenazolone derivatives via [3+1+1] cycloaddition of cyclopropenone derivatives, anilines, and elemental chalcogens. The cascade reaction involves the C?S, C?N, and N?S bond formation along with the cleavage of C?C bond. Both anilines and cyclopropenones are tolerated and give the corresponding products in 28–73% yields. (Figure presented.).

Micellar Systems as ''Supercages'' for Reactions of Geminate Radical Pairs. Magnetic Effects

The photochemistry of dibenzyl ketone (DBK) and other molecules capable of producing benzyl radicals and substituted benzyl radicals has been investigated in micellar systems.The cage effect (percent of unscavengeable radical pairs produced by photolysis) was measured under a variety of conditions, and the results are compared with those obtained in homogeneous organic solvents.For example, parameters such as mean occupancy of ketone, detergent type and concentration, O2 concentration, additives, temperature, applied magnetic field, and pressure have been varied and investigated as to their influence on the magnitude of cage effect.In addition to modifying its environment, structural modification of the DBK by incorporation of 2H and 13C isotopes, hydrophobic groups, and heavy atoms was performed to investigate the impact of these variations on the cage effect in micellar systems.Isotopic substitution of 2H or 13C leads to results on both the quantum yields for reactions and on the percent cage that were consistent with expectations of magnetic isotope effects.Hydrophobic groups substituted in the 4-position of DBK were found to cause a substantial increase in the cage effect and yet retain the magnetic-field-dependent character found in the parent DBK.Incorporation of Br in the 4-position of DBK was found to enhance the cage effect but at the same time cause the cage effect to become magnetic field independent.Substitution of α-naphthyl for phenyl in DBK also produced magnetic-field-independent behavior, in addition to a dramatic decrease in the efficiency of photolysis.