358681-53-5

Upstream product

• 6931-68-6 methyl 5-acetamido-2,4,7,8,9-penta-O-acetyl-3,5-dideoxy-D-glycero-D-galacto-2-nonulopyranosonate 
• 106-45-6 para-thiocresol 
• 358681-51-3 methyl (2-p-methylphenyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-β-D-galacto-2-thio-nonulopyranosid)onate 
• 100-39-0 benzyl bromide 
• 358681-52-4 (2R,4S,5R,6R)-5-Acetylamino-4-benzyloxy-2-p-tolylsulfanyl-6-((1S,2R)-1,2,3-tris-benzyloxy-propyl)-tetrahydro-pyran-2-carboxylic acid benzyl ester 

Downstream Products

• 358681-47-7 Acetic acid (2R,4S,5R,6R)-5-acetylamino-4-benzyloxy-2-p-tolylsulfanyl-6-((1S,2R)-1,2,3-tris-benzyloxy-propyl)-tetrahydro-pyran-2-ylmethyl ester 

Relevant academic research and scientific papers

Conversion of the carboxy group of sialic acid donors to a protected hydroxymethyl group yields an efficient reagent for the synthesis of the unnatural beta-linkage

New sialyl donors with a protected hydroxymethyl group at the anomeric center are over 1000 times more reactive than the normal ester containing sialylation reagent and give excellent yield (> 90%) with unusually high β-stereoselectivity in sialylation.