358971-40-1Relevant academic research and scientific papers
Modular Approach to Substituted Pyridoazepinones
Dorokhov, Valentin S.,Zard, Samir Z.
, p. 2164 - 2168 (2021)
Pyridoazepinones are potentially interesting structures, yet they are still underexploited in the medicinal chemistry field and hard to obtain synthetically. We present a general and flexible synthetic route to substituted pyridoazepinones, enabled by the xanthate addition-transfer process, which furnishes the target molecules from readily available starting materials in generally good yields. The method shows good functional group tolerance and allows the preparation of pyridoazepinone scaffolds on gram scale.
Pharmaceutical compositions containing azetidine derivatives, novel azetidine derivatives and their preparation
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, (2008/06/13)
The present invention relates to pharmaceutical compositions containing, as an active ingredient, at least one compound of formula: in which R1represents a radical —N(R4)R5, —N(R4)—CO—R5, —N(R4)—SO2R6or one of its pharmaceutically acceptable salts, to the novel derivatives of formula (I), to their pharmaceutically acceptable salts and to their preparation.
