358971-48-9

Basic information

• Product Name: Methanesulfonamide, N-(3,5-difluorophenyl)-
• CAS NO: 358971-48-9
• Molecular Formula: C7H7F2NO2S
• Molecular Weight: 207.201
• Mol File: 358971-48-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Methanesulfonamide, N-(3,5-difluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Methanesulfonamide, N-(3,5-difluorophenyl)-(358971-48-9)
• EPA Substance Registry System: Methanesulfonamide, N-(3,5-difluorophenyl)-(358971-48-9)

Safety Data

• Hazardous Substances Data: 358971-48-9(Hazardous Substances Data)

Upstream product

• 372-39-4 3,5-difluoroaniline 
• 124-63-0 methanesulfonyl chloride 

Downstream Products

• 358970-97-5 Drinabant 

Relevant articles and documents

Palladium-Catalyzed cascade sp2 c?H bond functionalizations allowing one-Pot access to 4?Aryl-1,2,3,4-tetrahydroquinolines from n?Allyl?N?arylsulfonamides

We have developed a palladium-catalyzed cascade reaction allowing an efficient synthesis of 4-aryl-1,2,3,4-tetrahydroquinolines from N-allyl-N-arylsulfonamides and benzenesulfonyl chlorides. In this transformation, two C(sp2)?C(sp3) bonds were formed via activation of C(sp2)?H bonds. The reaction proceeds using the easily accessible catalyst PdCl2, with Li2CO3 as inexpensive base and CuBr as additive, and tolerates a wide variety of substituents on both reaction partners.

NOVEL PRODUCT, METHOD AND INTERMEDIATES FOR THE PREPARATION OF AZETIDINE DERIVATIVES

The present invention relates to a novel method for the preparation of azetidine derivatives such as N-{1-[bis(4-chlorophenyl)methyl]azetidin-3-yl}-N-quinol-6-ylmethylsulfonamide and the dihydrochloride thereof and N-{1-[bis(4-chlorophenyl)methyl]azetidin