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2,2-Difluoroacetamide, a chemical compound with the molecular formula C2H3F2NO, is a clear, colorless liquid characterized by a pungent odor. It is a derivative of acetamide, featuring two fluorine atoms attached to the functional group. 2,2-DIFLUOROACETAMIDE is recognized for its utility as a solvent and an intermediate in organic synthesis, as well as its role in the production of pesticides and pharmaceuticals. Due to its moderately toxic nature, it requires careful handling and adherence to safety protocols.

359-38-6

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359-38-6 Usage

Uses

Used in Organic Synthesis:
2,2-Difluoroacetamide is used as a versatile intermediate in organic synthesis for the preparation of various chemical compounds. Its unique structure, with fluorine atoms attached to the acetamide group, provides specific reactivity and properties that are valuable in the synthesis of pharmaceuticals and other specialty chemicals.
Used in Solvent Applications:
As a solvent, 2,2-difluoroacetamide is employed in various chemical processes to dissolve and facilitate reactions with other substances. Its solubility properties make it suitable for use in a range of industrial applications, including the production of certain types of coatings and adhesives.
Used in Pesticide Manufacturing:
2,2-Difluoroacetamide is utilized in the manufacturing of pesticides, where its chemical properties contribute to the development of effective and targeted pest control agents. Its role in this industry is crucial for the creation of new and improved formulations that can address specific agricultural challenges.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 2,2-difluoroacetamide serves as a key intermediate in the synthesis of certain drugs. Its unique chemical structure allows for the development of new medicinal compounds with potential therapeutic benefits, contributing to advancements in healthcare and medicine.
Safety Precautions:
Given its moderately toxic nature, 2,2-difluoroacetamide requires careful handling and the implementation of proper safety measures. This includes the use of personal protective equipment, working in well-ventilated areas, and adhering to established guidelines for the safe storage and disposal of the compound.

Check Digit Verification of cas no

The CAS Registry Mumber 359-38-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,5 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 359-38:
(5*3)+(4*5)+(3*9)+(2*3)+(1*8)=76
76 % 10 = 6
So 359-38-6 is a valid CAS Registry Number.
InChI:InChI=1/C2H3F2NO/c3-1(4)2(5)6/h1H,(H2,5,6)

359-38-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,2-Difluoroacetamide

1.2 Other means of identification

Product number -
Other names 2,2-DIFLUOROACETAMIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:359-38-6 SDS

359-38-6Relevant academic research and scientific papers

METHOD FOR PREPARING SUBSTITUTED HETEROCYCLIC COMPOUNDS

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Page/Page column 14-15, (2019/12/15)

The present invention relates to a method for the production of substituted heterocyclic compounds of Formula (I) or of salts thereof.

Method for preparing a fluorinated organic compound

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Paragraph 0293-0294, (2014/06/11)

A method for preparing a fluorinated organic compound (II) from an organic compound (I) comprising at least one nucleofugal group Nu, and also a preparation of different specific organic compounds, in particular a fluoro-methylpyrazole compound. The method comprises: a reaction, in the presence of water, of the organic compound (I) and at least one salt providing at least one fluoride anion; and a replacement of at least one nucleofugal group Nu of the compound (I) with a fluorine atom, in order to obtain the fluorinated organic compound (II).

Electrochemical fluorination of benzamide and acetanilide in anhydrous HF and in acetonitrile

Shainyan,Danilevich,Grigor'eva,Chuvashev

, p. 513 - 517 (2007/10/03)

Electrochemical fluorination of benzamide in anhydrous hydrogen fluoride does not involve the amide group but occurs exclusively at the aromatic ring, yielding isomeric fluoro- and difluorobenzamides and 3,3,6,6-tetrafluoro-1,4- cyclohexadienecarboxamide.

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