35951-50-9

Usage

Uses

Used in Pharmaceutical Industry:
Lubimin is used as a pharmaceutical compound for its potential therapeutic properties. Its unique chemical structure allows it to interact with specific biological targets, making it a candidate for the development of new drugs.
Used in Chemical Research:
In the field of chemical research, Lubimin serves as a subject for studying the properties and reactions of sesquiterpenoids. This can lead to a better understanding of their potential applications and the development of new compounds with similar structures.
Used in Cosmetics Industry:
Lubimin may be used as an ingredient in the cosmetics industry, where its unique properties could contribute to the development of innovative skincare and beauty products.
Used in Agricultural Industry:
The potential application of Lubimin in the agricultural industry could involve its use as a natural compound for pest control or as a component in the development of new biopesticides.

InChI:InChI=1/C15H24O2/c1-10(2)12-4-5-15(8-12)11(3)6-14(17)7-13(15)9-16/h9,11-14,17H,1,4-8H2,2-3H3/t11-,12-,13-,14+,15+/m1/s1

Upstream product

• 150-97-0 D,L-mevalonic acid 
• 54878-25-0 (-)-Solavetivone 
• 35951-50-9 lubimin 
• 11139-99-4 epilubimin 
• 93198-33-5 (+/-)-<8,8-²H₂>solavetivone 

Downstream Products

• 35951-50-9 10-epi-lubimin 
• 55784-95-7 4-Bromo-benzoic acid (2R,5S,6S,10R)-2-isopropyl-10-methyl-8-oxo-spiro[4.5]dec-6-ylmethyl ester 

Relevant academic research and scientific papers

1H NMR Study of the Stereochemistry of Lubimin and Related Vetispirane Sesquiterpenoids

The stereochemistry at C-2 and C-10 in lubimin, 15-dihydrolubimin and 3-hydroxylubimin derivatives has been investigated by 1H NMR spectroscopy.Using parent compounds and acetyl derivatives (24 compounds) definitive spectroscopic assignments have been made.Nine oxidised derivatives (2- and 3-keto functionalisation) have also been investigated.The usefulness of diagnostic features in the spectra are illustrated and the conformational homogeneity of the series verified.

OXYSOLAVETIVONE. A NEW BIOSYNTHETIC PRECURSOR OF LUBIMIN IN POTATO

The title compound, isolated newly as a metabolite from solavetivone, was converted into lubimin in potato.

The biosynthesis of lubimin from [1-14C]isopentenyl pyrophosphate by cell-free extracts of potato tuber tissue inoculated with an elicitor preparation from Phytophthora infestans

A cell-free enzyme system, which catalyses the incorporation of radiolabel from [ 1 2-14C]isopentenyl pyrophosphate into the sesquiterpenoid phytoalexin lubimin, has been prepared from tuber tissue of Solanum tuberosum inoculated with an elicitor preparation from Phytophthora infestans. Biosynthesis of lubimin is optimum at pH 7. 3 2-7.5 and is dependent upon Mg2+ and NADPH. Lubimin labelling by cell-free enzyme system prepared from tissue 48 hr after treatment with elicitor rises rapidly to a maximum over the first 30 min of incubation and does not decline for a further 150 min. The biosynthetic capacity for lubimin in cell free extracts can be observed as early as 3 hr after inoculation of tuber tissue, and rises to a maximum at about 48 hr after treatment, declining thereafter. Lubimin labelling is inhibited by iodoacetamide, the effect of which is reversed by 3,3-dimethylallylpyrophosphate. Preliminary observations on the cell-free system show that it will also catalyse the incorporation of [2-14C]mevalonic acid into lubimin in the presence ofan ATP-generating system.

Structure of Epilubimin, Epioxylubimin, and Isolubimin, Spirovetivane Stress Metabolites in Diseased Potato

The isolation and structure elucidation of the title spirovetivane sesquiterpenes, stress metabolites produced in diseased potato tubers, are described.