54878-25-0Relevant academic research and scientific papers
NOVEL METHODS FOR PRODUCTION OF 5-EPI-β-VETIVONE, 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-2,6-DIEN-8-ONE, AND 2-ISOPROPYL-6,10-DIMETHYL-SPIRO[4.5]DECA-1,6-DIEN-8-ONE
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Page/Page column title page; 9; 13; 15; 17; 34-35, (2008/12/07)
The present invention is directed to novel methods for production of 5-epi-β-vetivone, 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4,5]deca-1,6-dien-8-one, which are useful for their fragrant qualities, in one embodiment the present invention describes a method for production of 5-epi-β-vetivone by the use of premnaspirodiene as starting material. In another embodiment the present invention describes a method for production of 2-isopropyl-6,10-dimethyl- spiro[4.5]deca-2,6-dien-8-one and 2-isopropyl-6,10-dimethyl-spiro[4.5]deca-1,6-dien-8-one by the use of premnaspirodiene as starting material. In yet another embodiment the present invention describes a novel method for production of premnaspirodiene from a terpene substrate.
Total synthesis of (-)-solavetivone using enantioselective copper-catalysed conjugate addition of Me3Al to a cyclohexa-2,5-dienone intermediate
Takemoto, Yoshiji,Kuraoka, Satoru,Ohra, Taiichi,Yonetoku, Yasuhiro,Iwata, Chuzo
, p. 1655 - 1656 (2007/10/03)
By applying a new enantioselective Cu-catalysed conjugate addition of Me3Al, (-)-solavetivone 1 is synthesized stereoselectively from cyclohexa-2,5-dienone 4, prepared from a chiral compound 6 using a regioselective HgII-mediated cyc
A General Synthetic Approach of Spirovetivanes. The Synthesis of (+/-)-Solavetivone, (+/-)-Hinesol, and Related Compounds
Murai, Akio,Sato, Shingo,Masamune, Tadashi
, p. 2276 - 2281 (2007/10/02)
The synthetic procedure leading to preparation of representative compounds, (+/-)-solavetivone and (+)-hinesol, of two classes of spirovetivanes, is described.The procedure involves Diels-Alder reaction of 4-substituted 5,6-dihydro-3,5-dimethylanisoles wi
Π-CYCLIZATION: THE SYNTHESIS OF (+/-)-SOLAVETIVONE AND (+/-)-HINESOL
Murai, Akio,Sato, Shingo,Masamune, Tadashi
, p. 1033 - 1036 (2007/10/02)
A general efficient approach leading to the total synthesis of (+/-)-solavetivone, (+/-)-hinesol, and related spirovetivanes, is described.The process involves stereoselective formation of the asymmetric center at C-7 by ?-cyclisation as a key step.
Total Synthesis of (+/-)-Solavetivone; X-Ray Crystal Structure of 2-Hydroxy-6,10-dimethylspirodec-6-en-8-one
Iwata, C.,Fusaka, T.,Fujiwara, T.,Tomita, K.,Yamada, M.
, p. 463 - 465 (2007/10/02)
(+/-)-Solavetivone (1) was synthesized by a new spiro-annelation reaction and a unique regio- and stereoselective reduction of the spiro-dienone (4) to give (5), the structure of which has been determined by X-ray crystallography.
