359610-36-9

Upstream product

• 21815-91-8 3-chlorobenzo[b]thiophen-2-carbonyl chloride 
• 359458-02-9 2-(3-chlorobenzo[b]thiophen-2-yl)-4-(4-nitrobenzylidene)oxazol-5(4H)-one 
• 371-40-4 4-fluoroaniline 
• 216985-67-0 2-(3-chlorobenzo[ b]thiophene-2-carboxamido)acetic acid 

Relevant academic research and scientific papers

Synthesis and antimicrobial activity of oxazolone, imidazolone and triazine derivatives containing benzothiophene

3-Chloro-1-benzothiophene-2-carbonylchloride (1) was allowed to react with glycine to give 3-chloro-1-benzothiophen-2-yl-carbonylaminoacetic acid (2). Various aldehydes were treated with compound (2) in acetic anhydride to get 1,3-oxazol-5-ones (3a-d). Th

Synthesis and antimicrobial activity of oxazolone, imidazolone and triazine derivatives containing benzothiophene

3-Chloro-1-benzothiophene-2-carbonyl chloride 1 was reacted with glycine in acetone to give 3-chloro-1- benzothiophen-2-yl-carbonylaminoacetic acid 2. Various aldehydes on treatment with compound 2 in acetic anhydride to gave 1,3-oxazol-5-ones