36004-54-3

Upstream product

• 500550-51-6 N-{2-[hydroxy(phenyl)methyl]phenyl}benzenesulfonamide 
• 881169-88-6 N-{2-[bromo(phenyl)methyl]phenyl}benzenesulfonamide 
• 94301-17-4 N-(2-benzoyl-phenyl)-benzenesulfonamide 
• 70-11-1 α-bromoacetophenone 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 41120-12-1 N,N-diphenacylaniline 
• 113385-73-2 N,N-bis(phenacyl)-4-methylaniline 
• 1000775-45-0 N,N-bis(phenacyl)-4-chloroaniline 
• 1426307-45-0 C₂₂H₁₈FNO₂ 
• 98-80-6 phenylboronic acid 
• 347839-76-3 N-(2-(hydroxymethyl)phenyl)methanesulfonamide 
• 5344-90-1 2-Aminobenzyl alcohol 
• 118-92-3 anthranilic acid 

Downstream Products

• 1418308-55-0 C₂₇H₂₁BF₂N₂ 

Relevant academic research and scientific papers

One-pot synthesis of 2-hydroxymethylindoles: via photoredox-catalyzed ketyl-ynamide coupling/1,3-allylic alcohol transposition

An efficient visible-light-mediated ketyl-ynamide coupling by employing ynamides bearing alkyl sulfonyl substituents to deliver eneindolin-3-ols has been developed. Subsequent 1,3-transposition of allylic alcohols in one pot is capable of synthesizing 2-hydroxymethylindoles in generally moderate to good yields. The synthetic utility of this protocol has also been demonstrated by the facile and practical synthesis of two bioactive molecules. The use of readily available substrates, a simple procedure and benign reaction conditions render this method a viable alternative for the synthesis of 2-hydroxymethylindoles. This journal is

Tandem addition/cyclization for synthesis of 2-aroyl benzofurans and 2-aroyl indoles by carbopalladation of nitriles

The first example of the palladium-catalyzed tandem addition/cyclization of 2-(2-acylphenoxy)acetonitriles with arylboronic acids has been developed, providing a new strategy for the synthesis of 2-aroyl benzofurans with excellent chemoselectivity and wid

Microwave Energized Synthesis of 2-Aroylindole Derivatives: Piperidine/DMF as an Effective Medium

A convenient and efficient protocol has been developed for the synthesis of 2-aroylindoles (3a, 3b, 3c, 3d, 3e, 3f, 3g, 3h, 3i, 3j) in good yields by the reaction of 2-aminoketones (1a, 1b, 1c) with phenacyl bromides (2a, 2b, 2c, 2d). The reaction success varied with different bases and solvents in both conventional and microwave methods. But finally, it was established that piperidine in DMF was an effective medium to carry out the reaction under microwave irradiation conditions.

Reaction of diphenacylanilines with 2-aminobenzophenone: An abnormal friedlander reaction yielding indoles

This article describes an abnormal Friedlander reaction between diphenacylaniline and 2-aminobenzophenone in the presence of a catalytic amount of (±)-camphorsulfonic acid yielding 2-aroyl-3-arylindoles in quantitative yield. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications to view the free supplemental file.

Benzene-fused BODIPYs: Synthesis and the impact of fusion mode

BODIPY derivatives with one or two benzene units fused at different positions are prepared using novel synthetic methods. The resulting dye 1 shows deep red fluorescence with a large Stokes shift. Dyes 2 and 3 are reported for the first time and 3 exhibits near infrared absorption. The impact of benzannulation at different positions of BODIPY is discussed, and the geometry and electronic structure are studied by DFT calculations.

Heterocycles from ylides. Part IX. A convenient synthesis of 1-sulfonyl-2,3-disubstituted 2,3-dihydroindoles

The reaction of sulfur ylides (1) with N-(2-bromomethylphenyl)benzenesulfonamides (4) gives 2,3-dihydroindoles (5) whose structure and stereochemistry were assigned on the basis of analytical and spectroscopic data. Some chemical transformations of 5 are