360048-15-3

Basic information

• Product Name: 1-(2'-deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2-pyrimidone
• Synonyms: 1-(2'-deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2-pyrimidone
• CAS NO: 360048-15-3
• Molecular Weight: 595.655
• Mol File: 360048-15-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2'-deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2-pyrimidone(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2'-deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2-pyrimidone(360048-15-3)
• EPA Substance Registry System: 1-(2'-deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2-pyrimidone(360048-15-3)

Safety Data

• Hazardous Substances Data: 360048-15-3(Hazardous Substances Data)

Upstream product

• 117032-49-2 4-(1,2,4-triazol-1-yl)-5'-O-(4,4'-dimethoxytriphenylmethyl)-3'-O-trimethylsilyl thymidine 
• 50-89-5 thymidine 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 109389-25-5 1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methyl-4-(1H-1,2,4-triazol-1-yl)pyrimidin-2(1H)-one 
• 40615-39-2 5'-O-(4-4'-dimethoxytrityl)thymidine 
• 288-88-0 1,2,4-Triazole 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 937376-82-4 4-(2-cyanoethyl)seleno-5'-O-(4,4'-dimethoxytriphenylmethyl)thymidine 
• 101712-10-1 1-(2'-deoxy-5'-O-dimethoxytrityl-β-D-ribofuranosyl)-5-methyl-4-(1,2,4-triazol-1-yl)-2-pyrimidone 3'-(N,N-diisopropylamido)-β-cyanoethylphosphite 

Relevant articles and documents

Nucleobase Modifiers Identify TET Enzymes as Bifunctional DNA Dioxygenases Capable of Direct N-Demethylation

TET family enzymes are known for oxidation of the 5-methyl substituent on 5-methylcytosine (5mC) in DNA. 5mC oxidation generates the stable base 5-hydroxymethylcytosine (5hmC), starting an indirect, multi-step process that ends with reversion of 5mC to un

Oxygen replacement with selenium at the thymidine 4-position for the Se base pairing and crystal structure studies

The T-A and C-G base pairing and stacking allow the formation of the stable DNA duplex structure for genetic information storage, transcription, and replication. To replace the oxygen of the nucleotide nucleobases with selenium for the studies of the base