36044-31-2Relevant academic research and scientific papers
Synthesis of 2-Iodoazulenes by the Iododeboronation of Azulen-2-ylboronic Acid Pinacol Esters with Copper(I) Iodide
Narita, Masahiro,Murafuji, Toshihiro,Yamashita, Saki,Fujinaga, Masayuki,Hiyama, Kumiko,Oka, Yurie,Tani, Fumito,Kamijo, Shin,Ishiguro, Katsuya
, p. 1298 - 1303 (2018)
Azulen-2-ylboronic acid pinacol ester, prepared by iridium-catalyzed C-H borylation of azulene, efficiently underwent iododeboronation with a stoichiometric amount of copper(I) iodide. This reaction allowed the synthesis of 2-iodoazulene in only two steps starting from azulene. This methodology was successfully applied to analogous azulenes.
Synthesis of 2-aminoazulene derivatives. Nucleophilic and palladium-catalyzed amination of 2-substituted azulene
Yokoyama, Ryuji,Ito, Shunji,Okujima, Tetsuo,Kubo, Takahiro,Yasunami, Masafumi,Tajiri, Akio,Morita, Noboru
, p. 8191 - 8198 (2007/10/03)
Amination of 2-substituted azulene was carefully examined using several types of amines, and the scope and limitation of substrates and reagents in these direct nucleophilic aminations were found. The synthesis of 2-aminoazulenes was successfully achieved by the reaction of 2-bromoazulene with several amines via palladium-catalyzed amination.
