360778-68-3

Upstream product

• 223906-33-0 ((R)-2-hydroxy-2-methyl-1-phenyl-propyl)-carbamic acid tert-butyl ester 
• 110480-87-0 (R)-1-amino-2-methyl-1-phenyl-propan-2-ol 
• 141190-94-5 (R)-N-(tert-butoxycarbonyl)phenylglycine methyl ester 
• 875-74-1 (R)-phenylglycine 
• 24461-61-8 (R)-Phenylglycine methyl ester 

Downstream Products

• 360778-83-2 (R)-[2-(tert-Butyl-dimethyl-silanyloxy)-3,5-dimethoxy-4-methyl-phenyl]-((R)-2-hydroxy-2-methyl-1-phenyl-propylamino)-acetic acid methyl ester 
• 360778-72-9 (3R,5R)-3-(7-Hydroxy-6-methoxymethoxy-benzo[1,3]dioxol-4-yl)-6,6-dimethyl-5-phenyl-morpholin-2-one 
• 360778-80-9 methanesulfonic acid 6-(6,6-dimethyl-2-oxo-5-phenylmorpholin-3-yl)-2,4-dimethoxy-3-methylphenyl ester 
• 360778-82-1 (R)-(2-Hydroxy-3,5-dimethoxy-4-methyl-phenyl)-((R)-2-hydroxy-2-methyl-1-phenyl-propylamino)-acetic acid methyl ester 
• 360778-77-4 3-(2-hydroxy-3,5-dimethoxy-4-methylphenyl)-6,6-dimethyl-5-phenylmorpholin-2-one 
• 360778-69-4 agent lactone 

Relevant academic research and scientific papers

Synthesis of optically active α-arylglycines: Stereoselective Mannich-type reaction with a new chiral template

Mannich-type reaction of phenols with iminolactone 4, readily prepared from commercially available phenylglycine, proceeded with high stereoselectivity to give α-arylglycine derivatives. The reaction was also applicable to other electron-rich aromatic compounds and aryl boronic acids. These adducts could be readily converted to the corresponding optically active α-arylglycines.