360796-63-0Relevant academic research and scientific papers
Practical Synthesis of Sultams via Sulfonamide Dianion Alkylation: Application to the Synthesis of Chiral Sultams
Lee, Jaemoon,Zhong, Yong-Li,Reamer, Robert A.,Askin, David
, p. 4175 - 4177 (2003)
(Equation presented) A practical synthesis of sultams was developed via intramolecular sulfonamide dianion alkylation. This method has been applied toward the synthesis of chiral sultams, which are synthetically valuable as chiral auxiliaries.
Coordination of (β-N-sulfonylaminoalkyl)phosphines and their analogous arsines to PdII and PtII. Application of the Pd-complexes as chiral catalysts in asymmetric hydrosilylation of 1,3-dienes
Gustafsson,Bergqvist,Frejd
, p. 1452 - 1457 (2007/10/03)
Optically active ligands 2 and 3 were synthesised from phenylglycine and the coordination of ligand 2 to PdCl2(CH3CN)2 and PtCl2(C6H5CN)2 was studied with 1H, 31P and 15N-1H-HMQC NMR spectroscopy. The results indicated P,O rather than P,N bidentate coordination. Both ligands were tested in the palladium catalysed hydrosilylation of cyclic 1,3-dienes. Asymmetric induction of up to 84% (≤25% yield), which is the hitherto highest reported ee value for asymmetric hydrosilylation of 1,3-dienes, was achieved as measured on the allylic alcohols formed after ethanolysis-oxidation of the initially formed allylic silanes.
