Practical Synthesis of Sultams via Sulfonamide Dianion Alkylation: Application to the Synthesis of Chiral Sultams

DOI: 10.1021/ol0356183

Source and publish data:

Organic Letters p. 4175 - 4177 (2003)

Update date:2022-08-04

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Authors:

Lee, Jaemoon

Zhong, Yong-Li

Reamer, Robert A.

Askin, David

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Article abstract of DOI:10.1021/ol0356183

(Equation presented) A practical synthesis of sultams was developed via intramolecular sulfonamide dianion alkylation. This method has been applied toward the synthesis of chiral sultams, which are synthetically valuable as chiral auxiliaries.

Full text of DOI:10.1021/ol0356183

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