361456-07-7

Upstream product

• 2746-25-0 p-Methoxybenzyl bromide 
• 361456-04-4 3-(4-methoxy-phenyl)-5-(2-trimethylsilanyl-ethoxy)-1H-pyrrolo[3,2-b]pyridine 
• 361456-00-0 [3-nitro-6-(2-trimethylsilanyl-ethoxy)-pyridin-2-yl]-acetonitrile 
• 361456-02-2 3-iodo-5-(2-trimethylsilanyl-ethoxy)-1H-pyrrolo[3,2-b]pyridine 
• 361456-01-1 5-(2-trimethylsilanyl-ethoxy)-1H-pyrrolo[3,2-b]pyridine 
• 135900-24-2 5-nitro-2-(2-trimethylsilanylethoxy)pyridine 
• 5720-07-0 4-methoxyphenylboronic acid 
• 2916-68-9 2-(Trimethylsilyl)ethanol 
• 4548-45-2 2-chloro-5-nitropyridine 

Relevant academic research and scientific papers

Cell permeability as a parameter for lead generation in the protein Tyrosine kinase inhibition field

Based on the inverse relationship between polar surface area and cell permeability and capitalizing on the properties of pyrrolopyrimidines 1 as protein tyrosine kinase inhibitors, pyrrolopyridones 2 were designed and synthesized as potential leads for th