3615-56-3

Usage

Uses

Used in Pharmaceutical Industry:
D-(+)-Sorbose is used as an intermediate in the synthesis of various pharmaceutical compounds for its ability to serve as a building block in the production of drugs. Its unique stereochemistry allows it to be a key component in the development of new medications.
Used in Food and Beverage Industry:
D-(+)-Sorbose is used as a sweetener and flavor enhancer for its natural sugar-like taste and ability to improve the taste profile of food and beverages. Its low caloric content and reduced impact on blood sugar levels make it a preferred choice for health-conscious consumers.
Used in Cosmetics Industry:
D-(+)-Sorbose is used as a humectant and moisturizing agent in cosmetic products for its ability to retain moisture and improve skin hydration. Its gentle and non-irritating properties make it suitable for use in skincare formulations.
Used in Biotechnology:
D-(+)-Sorbose is used in biotechnological applications for its role in the production of biofuels and other bio-based materials. Its potential as a renewable resource and its ability to be fermented make it a valuable component in the development of sustainable technologies.
Used in Research and Development:
D-(+)-Sorbose is used as a research compound for studying the properties and applications of sugar alcohols and their derivatives. Its unique stereochemistry provides valuable insights into the behavior of chiral molecules and their interactions with biological systems.

InChI:InChI=1/C6H12O6/c7-2-6(11)5(10)4(9)3(8)1-12-6/h3-5,7-11H,1-2H2/t3-,4+,5-,6+/m1/s1

Upstream product

• 453-17-8 D-Glyceraldehyde 
• 6027-89-0 L-gulose 
• 59-23-4 D-Galactose 
• 214490-56-9 peracetylated sorbose 
• 6706-59-8 L-Sorbitol 
• 5978-95-0 D-idose 
• 4205-23-6 D-gulose 
• 97833-77-7 Acetic acid (1S,2R)-2-acetoxy-1-((R)-1,2-diacetoxy-ethyl)-4-hydroxy-3-oxo-butyl ester 
• 16299-15-3 1,2,3,4,6,-penta-O-acetyl-α-D-idopyranose 
• 57-48-7 D-Fructose 
• 56-82-6 Glyceraldehyde 
• 2595-98-4 D-talose 
• 3891-58-5 tetra-O-acetyl-D-xylose 
• 492-62-6 alpha-D-glucopyranose 

Downstream Products

• 56196-14-6 trimethylsilylether of sorbose O-methyloxime 
• 64-18-6 formic acid 
• 488-45-9 L-iditol 
• 6706-59-8 L-Sorbitol 
• 461425-83-2 3-bromo-4-isopropylbenzylaldehyde 
• 7726-97-8 1,4-anhydro-D-glucitol 
• 7726-97-8 1,4-anhydro-D-glucitol 
• 20221-50-5 1,2,5,6-hexanetetrol 
• 5978-95-0 D-idose 
• 4205-23-6 D-gulose 
• 488-31-3 L-arabinaric acid 
• 57-48-7 fructose 
• 1232836-54-2 1,3,4,6-tetra-O-benzoyl-α-L-fructofuranosyl acetate 

Relevant academic research and scientific papers

Hydroxyapatite-Supported Polyoxometalates for the Highly Selective Aerobic Oxidation of 5-Hydroxymethylfurfural or Glucose to 2,5-Diformylfuran under Atmospheric Pressure

(NH4)5H6PV8Mo4O40 supported on hydroxyapatite (HAP) (PMo4V8/HAP (n)) was prepared through the ion exchange of hydroxy groups. This ion exchange favored the oxidative conversion of 5-hydroxymethylfurfural (5-HMF) to 2,5-diformylfuran (DFF) in a one-pot cascade reaction with 96.0 % conversion and 83.8 % yield under 10 mL/min of O2 flow. PMo4V8/HAP (31) was used to explore the production of DFF directly from glucose with the highest yield of 47.9 % so far under atmospheric oxygen, whereas the yield of DFF increased to 54.7 % in a one-pot and two-step reaction. These results indicated that the active sites in PMo4V8/HAP (31) retained their activities without any interference toward one another, which enabled the production of DFF in a more cost-saving way by only using oxygen and one catalyst in a one-step reaction. Meanwhile, the rigid structure of HAP and strong interaction in PMo4V8/HAP (31) allowed this catalyst to be reused for at least six times with high stability and duration.

Few-Unit-Cell MFI Zeolite Synthesized using a Simple Di-quaternary Ammonium Structure-Directing Agent

Synthesis of a pentasil-type zeolite with ultra-small few-unit-cell crystalline domains, which we call FDP (few-unit-cell crystalline domain pentasil), is reported. FDP is made using bis-1,5(tributyl ammonium) pentamethylene cations as structure directing agent (SDA). This di-quaternary ammonium SDA combines butyl ammonium, in place of the one commonly used for MFI synthesis, propyl ammonium, and a five-carbon nitrogen-connecting chain, in place of the six-carbon connecting chain SDAs that are known to fit well within the MFI pores. X-ray diffraction analysis and electron microscopy imaging of FDP indicate ca. 10 nm crystalline domains organized in hierarchical micro-/meso-porous aggregates exhibiting mesoscopic order with an aggregate particle size up to ca. 5 μm. Al and Sn can be incorporated into the FDP zeolite framework to produce active and selective methanol-to-hydrocarbon and glucose isomerization catalysts, respectively.

Method for preparing lactic acid through catalytically converting carbohydrate

The invention relates to a method for preparing lactic acid through catalytically converting carbohydrate, and in particular, relates to a process for preparing lactic acid by catalytically convertingcarbohydrate under hydrothermal conditions. The method disclosed by the invention is characterized by specifically comprising the following steps: 1) adding carbohydrate and a catalyst into a closedhigh-pressure reaction kettle, and then adding pure water for mixing; 2) introducing nitrogen into the high-pressure reaction kettle to discharge air, introducing nitrogen of 2 MPa, stirring and heating to 160-300 DEG C, and carrying out reaction for 10-120 minutes; 3) putting the high-pressure reaction kettle in an ice-water bath, and cooling to room temperature; and 4) filtering the solution through a microporous filtering membrane to obtain the target product. The method can realize high conversion rate of carbohydrate and high yield of lactic acid, and has the advantages of less catalyst consumption, good circularity, small corrosion to reaction equipment and the like.

Bi-Functional Magnesium Silicate Catalyzed Glucose and Furfural Transformations to Renewable Chemicals

Bio-refinery is attracting significant interest to produce a wide range of renewable chemicals and fuels from biomass that are alternative to fossil fuel derived petrochemicals. Similar to petrochemical industries, bio-refinery also depends on solid zeolite catalysts. Acid-base catalysis plays pivotal role in producing a wide range of chemicals from biomass. Herein, the Mg framework substituted MTW zeolite is synthesized and explored in the valorisation of glucose and furfural. Bi-functional (acidic and basic) characteristics are confirmed using pyridine adsorbed FT?IR analysis and NH3 and CO2 temperature-programmed desorption techniques. Textural properties and morphological information are retrieved from N2-sorption, X-ray photoelectron spectroscopy, and electron microscopy. The activity of the catalyst is demonstrated in the selective isomerisation of glucose to fructose in ethanol. Glucose is converted to methyl lactate in high yield using the same catalyst. Further, the bi-functional activity of this catalyst is demonstrated in the production of fuel precursor by the reaction of furfural and isopropanol. Mg?MTW zeolite exhibits excellent activity in the production of all these chemicals and fuel derivative. The catalyst exhibits no significant loss in the activity even after five recycles. One simple catalyst affording three renewable synthetic intermediates from glucose and furfural will attract significant attention to catalysis researchers and industrialists.

PROCESSES FOR PREPARING SORBOSE FROM GLUCOSE

Processes for converting glucose to sorbose with tailored selectivity. The processes include contacting glucose with a silica-containing structure that includes a zeolite having a topology of a 10-membered ring or smaller and Lewis acidic M4+ framework centers, wherein M is Ti, Sn, Zr, or Hf. Contacting the glucose is conducted under reaction conditions sufficient to isomerize the glucose to sorbose.

Method for preparing fructose (by machine translation)

The method comprises the following steps: (1) reacting glucose with a catalyst in the presence of alcohol and carrying out reaction to obtain fructose-containing product; wherein the weight ratio of the glucose to the mixture of the titanium silicalite molecular sieve and the tin-silicon molecular sieve 50 - 600 is below 30 °C: (100 °C 0.1 - 6 1 1 - 10h) The method disclosed by the invention has high glucose conversion rate and fructose yield. (by machine translation)

Characterization of alditol oxidase from Streptomyces coelicolor and its application in the production of rare sugars

A synthetic platform for the cascade synthesis of rare sugars using Escherichia coli whole cells was established. In the cascade, the donor substrate dihydroxyacetone phosphate (DHAP) was generated from glycerol by glycerol kinase (GK) and glycerol phosphate oxidase (GPO). The acceptor D-glyceraldehyde was directly produced from glycerol by an alditol oxidase. Then, the aldol reaction between DHAP and D-glyceraldehyde was performed by L-rhamnulose-1-phosphate aldolase (RhaD) to generate the corresponding sugar-1-phosphate. Finally, the phosphate group was removed by fructose-1-phosphatase (YqaB) to obtain the rare sugars D-sorbose and D-psicose. To accomplish this goal, the alditol oxidase from Streptomyces coelicolor (AldOS.coe) was expressed in E. coli and the purified AldOS.coe was characterized. Furthermore, a recombinant E. coli strain overexpressing six enzymes including AldOS.coe was constructed. Under the optimized conditions, it produced 7.9 g/L of D-sorbose and D-psicose with a total conversion rate of 17.7% from glycerol. This study provides a useful and cost-effective method for the synthesis of rare sugars.

Role of the Strong Lewis Base Sites on Glucose Hydrogenolysis

This work reports the individual role of strong Lewis base sites on catalytic conversion of glucose hydrogenolysis to acetol/lactic acid, including glucose isomerisation to fructose and pyruvaldehyde rearrangement/hydrogenation to acetol/lactic acid. Las

A catalyzed by a chemical method, a method of glucose isomerization to fructose

The invention discloses a chemical method for catalyzing glucose into fructose through isomerization, and relates to fructose. The method comprises the following steps: mixing a water solution containing Mg(NO3)2.6H2O, Al(NO3)3.6H2O, and Zr(NO3)4.5H2O/Sn(NO3).6H2O/Cu(NO3)2.3H2O with a NaOH water solution and a Na2CO3 water solution, wherein the metal molar mass ratio of Mg:Al:M is equal to 3:1:1, M represents Zr, Sn, or Cu, pH is 8 to 8, and the temperature is 60 DEG C; carrying out aging on the precipitate in the mother liquid, then carrying out static crystallization, drying so as to obtain the trinary metal hydrotalcite, adding the trinary metal hydrotalcite into a glucose solution to carry out reactions, filtering so as to obtain isomerized glucose solution and a solid hydrotalcite catalyst, recycling the catalyst, and finally subjecting the filtrate to vacuum rotation evaporation so as to obtain a condensed fructose liquid, wherein the weight ratio of the trinary metal hydrotalcite to the glucose to solvent (water) is (1-4):(1-10):40.

Catalytic effect of aluminium chloride on the example of the conversion of sugar model compounds

Abstract In this work, the catalytic effect of the Bronsted acid hydrochloric acid, the Bronsted base sodium hydroxide and the Lewis acid AlCl3 on the conversion of biomass derived carbohydrates is investigated. On the example of the glycolaldehyde conversion, it is shown that the Lewis acid catalyses the ketol-endiol-tautomerism, the dehydration, the retro-aldol-reaction and the benzilic-acid-rearrangement. The main products are C4- and C6-carbohydrates as well as their secondary products 2-hydroxybut-3-enoic acid 1 and several furans. Under the same reaction conditions hydrochloric acid catalyzes mainly the dehydration and sodium hydroxide the tautomerism and subsequent aldolization.