361543-07-9

Basic information

• Product Name: Azido-PEG8-azide
• Synonyms: Azido-PEG8-azide;N3-PEG8-N3
• CAS NO: 361543-07-9
• Molecular Formula: C₁₈H₃₆N₆O₈
• Molecular Weight: 464.52
• Mol File: 361543-07-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Solubility: Soluble in Water, DMSO, DCM, DMF
• CAS DataBase Reference: Azido-PEG8-azide(CAS DataBase Reference)
• NIST Chemistry Reference: Azido-PEG8-azide(361543-07-9)
• EPA Substance Registry System: Azido-PEG8-azide(361543-07-9)

Safety Data

• Hazardous Substances Data: 361543-07-9(Hazardous Substances Data)

Usage

Description

Azido-PEG8-azide is a aqueous soluble, homebifunctional PEG reagent The azide (N3) group cis very reactive with alkyne, such as BCN, DBCO via Click Chemistry to yield a stable triazole moiety

Upstream product

• 3386-18-3 nonaethylene glycol 
• 55489-58-2 triethylene glycol monobenzyl ether 
• 80322-82-3 triethyleneglycol dimesylate 
• 105891-55-2 C₃₂H₅₀O₁₀ 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 

Relevant articles and documents

Synthesis and analysis of polyethylene glycol linked P-glycoprotein-specific homodimers based on (-)-stipiamide

A series of five homodimeric polyethylene glycol (PEG) linked homodimers based on the multidrug resistance reversal agent (-)-stipiamide were made and tested for their ability to interact with P-glycoprotein, the protein responsible for multidrug resistance, using ATPase and photoaffinity displacement assays. Key reactions include a new alkoxide-mesylate displacement for the assembly of the PEG linkers and a double Sonogashira coupling reaction.