361543-12-6

Basic information

• Product Name: PEODA₁₃
• Synonyms: PEODA₁₃
• CAS NO: 361543-12-6
• Molecular Weight: 588.737
• Mol File: 361543-12-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: PEODA₁₃(CAS DataBase Reference)
• NIST Chemistry Reference: PEODA₁₃(361543-12-6)
• EPA Substance Registry System: PEODA₁₃(361543-12-6)

Safety Data

• Hazardous Substances Data: 361543-12-6(Hazardous Substances Data)

Upstream product

• 361543-08-0 1,2-bis-{2-[2-(2-{2-[2-(2-azido-ethoxy)-ethoxy]-ethoxy}-ethoxy)-ethoxy]-ethoxy}-ethane 
• 112-27-6 2,2'-[1,2-ethanediylbis(oxy)]bisethanol 
• 361543-06-8 C₄₀H₆₆O₁₄ 
• 80322-82-3 triethyleneglycol dimesylate 
• 17598-96-8 poly(ethylene glycol) 600 
• 57671-28-0 2-(2-{2-[2-(2-benzyloxyethoxy)ethoxy]ethoxy}ethoxy)ethanol 
• 4792-15-8 Pentaethylene glycol 

Relevant articles and documents

PEGylated atorvastatin derivative and preparation method thereof

The invention relates to a PEGylated atorvastatin derivative and a preparation method thereof. The method mainly comprises the following steps: 1) activating an end group of PEG; 2) enabling the activated PEG to react with atorvastatin to obtain an atorvastatin analogue. The structure of the atorvastatin analogue is: Atorvastatin-L-PEG-L-Atorvastatin, wherein Atorvastatin is atorvastatin; L is anester bond, an amido bond or other linking group; the PEG is residue of monodisperse polyethylene glycol; the structural formula of the atorvastatin analogue is shown in the description, where n is aninteger between 1 and 24. The preparation method has the advantages of short flow, easiness and convenience in reaction operation, few side reactions, low cost, high reaction selectivity, easiness inpurification and higher yield.