36159-49-6Relevant academic research and scientific papers
Conformational effects on lipase-mediated acylations of 2-substituted cyclohexanols
Tanikaga, Rikuhei,Matsumoto, Yoshimasa,Sakaguchi, Maki,Koyama, Yohei,Ono, Kentaro
, p. 6781 - 6783 (2007/10/03)
Lipase-mediated acetylations of trans- and cis-2-substituted cyclohexanols gave the corresponding (1R)-cyclohexyl acetates and (1S)-cyclohexanols in high yields and ee, but c-4-tert-butyl-c-2-ethenyl-r-1-cyclohexanol was unreactive owing to the steric interaction between the axial OH group and the axial H atoms at the 3- and 5-positions. In the cis-isomer the OH group occupies an equatorial position to bind to the lipase, and less bulky axial alkenyl and alkynyl groups might not so much prevent acetylations than an alkyl group.
Olefin isomerization by a ruthenium carbenoid complex. Cleavage of allyl and homoallyl groups
Cadot, Christine,Dalko, Peter I,Cossy, Janine
, p. 1839 - 1841 (2007/10/03)
Ruthenium-carbenoid catalysts such as Grubbs' complex I mediate efficiently the isomerization of β,γ-unsaturated ethers and amines to the corresponding vinyl ethers and enamines. This reaction can be useful in the deprotection of allyl and homoallyl ethers as well as amines.
