36160-88-0Relevant academic research and scientific papers
Discovery of potent nitrotriazole-based antitrypanosomal agents: In vitro and in vivo evaluation
Papadopoulou, Maria V.,Bloomer, William D.,Rosenzweig, Howard S.,O'Shea, Ivan P.,Wilkinson, Shane R.,Kaiser, Marcel,Chatelain, Eric,Ioset, Jean-Robert
, p. 6467 - 6476 (2015)
3-Nitro-1H-1,2,4-triazole- and 2-nitro-1H-imidazole-based amides with an aryloxy-phenyl core were synthesized and evaluated as antitrypanosomal agents. All 3-nitrotriazole-based derivatives were extremely potent anti-Trypanosoma cruzi agents at sub nM con
