3619-73-6

Usage

Chemical Properties

Colorless liquid

InChI:InChI=1/C7H16N2/c1-2-9-6-3-4-8-5-7-9/h8H,2-7H2,1H3

Upstream product

• 505-66-8 1,4-Diazacycloheptane 
• 75-03-6 ethyl iodide 
• 61903-11-5 N-acetylhomopiperizine 
• 1609534-99-7 1-(benzyl carboxy)-4-ethyl-homopiperazine 
• 117009-97-9 benzyl 1,4-diazepane-1-carboxylate 

Downstream Products

• 530098-49-8 4-ethylhomopiperazin-1-ylacetate 
• 1035270-54-2 N-[5-[2-(3,5-dimethoxyphenyl)ethyl]-2H-pyrazol-3-yl]-5-(4-ethyl-1,4-diazepan-1-yl)pyrazine-2-carboxamide 
• 1177252-48-0 1-[(1-benzyl-1H-tetrazol-5-yl)(4-fluorophenyl)methyl]-4-ethyl-1,4-diazepane 
• 1609535-02-5 1,1-diethyl-4-(phenyl-4-benzyloxy)-homopiperazinium tosylate 
• 1609534-96-4 1,1-diethyl-4-(phenyl-4-hydroxy)-homopiperazinium tosylate 
• 1609535-00-3 1-(phenyl-4-benzyloxy)-4-ethyl-homopiperazine 
• 1265396-99-3 methyl 2-(2-(4-ethyl-1,4-diazepan-1-yl)-4-methyl-6-p-tolylpyrimidin-5-yl)pentanoate 

Relevant academic research and scientific papers

METHOD FOR USE OF HOMOPIPERAZINIUM COMPOUNDS IN THE TREATMENT OF CANCER

The present disclosure relates to a method for treating cancer comprising administering to a patient in need thereof an effective amount of a compound having the formula: (Formula (I)) wherein R1, R2, Ya, Xa, and J- are as defined herein.

COMBINATION THERAPY AND METHODS FOR THE TREATMENT OF RESPIRATORY DISEASES

The present disclosure relates to novel combination comprising a homopiperazinium compound having the formula (I): wherein J is a counter ion,; and one or more agents for treating or preventing the pulmonary diseases, for use and method for the treatment or prevention of respiratory diseases. Also provided are novel compounds and intermediates as well as processes for preparing same.

NOVEL COMPOUNDS

There is provided a compound of formula (I): or a pharmaceutically acceptable salt thereof. There are also provided processes for the manufacture of a compound of Formula 1, and the use of a compound of Formula 1 as a medicament and in the treatment of cancer.

Benzoheterocyclic derivatives

A benzoheterocyclic derivative of the following formula [1]: and pharmaceutically acceptable salts thereof, which show excellent anti-vasopressin activity, vasopressin agonistic activity and oxytocin antagonistic activity, and are useful as a vasopressin antagonist, vasopressin agonist or oxytocin antagonist.

Benzoheterocyclic derivatives

PCT No. PCT/JP95/01124 Sec. 371 Date Nov. 13, 1996 Sec. 102(e) Date Nov. 13, 1996 PCT Filed Jun. 7, 1995 PCT Pub. No. WO95/34540 PCT Pub. Date Dec. 21, 1995A benzoheterocyclic derivative of the following formula [1]: and pharmaceutically acceptable salts