362-55-0

Basic information

• Product Name: Benzenemethanol, 2-chloro-a-(4-fluorophenyl)-
• CAS NO: 362-55-0
• Molecular Formula: C13H10ClFO
• Molecular Weight: 236.673
• Mol File: 362-55-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzenemethanol, 2-chloro-a-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanol, 2-chloro-a-(4-fluorophenyl)-(362-55-0)
• EPA Substance Registry System: Benzenemethanol, 2-chloro-a-(4-fluorophenyl)-(362-55-0)

Safety Data

• Hazardous Substances Data: 362-55-0(Hazardous Substances Data)

Usage

General Description

Benzenemethanol, 2-chloro-a-(4-fluorophenyl)- is a chemical compound with the molecular formula C13H11ClF. It is a derivative of benzenemethanol with a 2-chloro and 4-fluorophenyl substitution. Benzenemethanol, 2-chloro-a-(4-fluorophenyl)- is used in the synthesis of pharmaceuticals and agrochemicals, as well as in research and development. It has been found to have potential biological activity and is being studied for its potential use in the treatment of various medical conditions. However, it is important to handle this compound with caution due to its potential hazards and toxicity.

Upstream product

• 89-98-5 2-chloro-benzaldehyde 
• 352-13-6 4-flourophenylmagnesium bromide 
• 694-80-4 2-bromo-1-chlorobenzene 
• 459-57-4 4-fluorobenzaldehyde 
• 1806-23-1 o-chlorophenyl p-fluorophenyl ketone 
• 15842-76-9 (2-chloro-phenyl)-trimethyl-silane 

Downstream Products

• 1323396-16-2 C₁₃H₉BrClF 

Relevant articles and documents

Bu4N+ alkoxide-initiated/autocatalytic addition reactions with organotrimethylsilanes

The use of Me3SiO-/Bu4N+ as a general activator of organotrimethylsilanes for addition reactions has been established. The broad scope of the method offers trimethylsilanes (including acetate, allyl, propargyl, benzyl, dithiane, heteroaryl, and aryl derivatives) as bench-stable organometallics that can be readily utilized as carbanion equivalents for synthesis. Reactions are achieved at rt without the requirement of specialized precautions that are commonplace for other organometallics.

BENZENE DERIVATIVES,PROCESS FOR PREPARING THE SAME AND USE THEREOF

Novel benzene derivatives represented by the formula (I) : wherein R1, R4 and R6 each independently represents a hydrogen atom, a halogen atom or a hydrocarbon group, R2 represents a hydrocarbon group or a heterocyclic group, R3 represents a hydrocarbon group, NR7'R7 or OR8 (wherein R7' represents a hydrogen atom or a hydrocarbon group, R7 represents a non-aromatic group, or R7' and R7 may form a ring with the adjacent nitrogen atom, and R8 represents a hydrocarbon group or a heterocyclic group), R5 represents a hydrocarbon group or a heterocyclic group (except for a quinolyl group), R5' represents a hydrogen atom, or a hydrocarbon group, or R5 and R5' may form a ring with the adjacent nitrogen atom, and R5" represents a hydrogen atom or a hydrocarbon group, which have vanilloid receptor agonist activity and are useful as a drug such as an analgesic and an agent for preventing and/or treating urinary frequency and/or urinary incontinence.