36209-71-9

Basic information

• Product Name: N-acetyl-3,4-methylenedioxyamphetamine hydrochloride
• Synonyms: N-acetyl-3,4-methylenedioxyamphetamine hydrochloride;(±)-N-Acetyl-3,4-methylenedioxyamphetamine
• CAS NO: 36209-71-9
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.25
• Mol File: 36209-71-9.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 417.6°Cat760mmHg
• Flash Point: 206.4°C
• Appearance: /
• Density: 1.169g/cm³
• Vapor Pressure: 3.5E-07mmHg at 25°C
• Refractive Index: 1.54
• PKA: 15.96±0.46(Predicted)
• CAS DataBase Reference: N-acetyl-3,4-methylenedioxyamphetamine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: N-acetyl-3,4-methylenedioxyamphetamine hydrochloride(36209-71-9)
• EPA Substance Registry System: N-acetyl-3,4-methylenedioxyamphetamine hydrochloride(36209-71-9)

Safety Data

• Hazardous Substances Data: 36209-71-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H15NO3/c1-8(13-9(2)14)5-10-3-4-11-12(6-10)16-7-15-11/h3-4,6,8H,5,7H2,1-2H3,(H,13,14)

Upstream product

• 4764-17-4 3,4-methylenedioxyamphetamine 
• 108-24-7 acetic anhydride 
• 5438-41-5 2-nitro-1-(3,4-methylenedioxyphenyl)-1-propene 
• 87095-03-2 5-(2-nitropropyl)benzo[d][1,3]dioxole 
• 5438-41-5 5-(2-nitroprop-1-enyl)benzo[d][1,3]dioxole 
• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 

Downstream Products

• 14089-52-2 3,4-methylenedioxyethylamphetamine 

Relevant articles and documents

Transformation of oximes of phenetyl ketone derivatives to quinolines and azaspirotrienones catalyzed by tetrabutylammonium perrhenate and trifluoromethanesulfonic acid

Phenethyl ketone oximes are converted to quinolines by the treatment with tetrabutylammonium perrhenate, trifluoromethanesulfonic acid, and chloranil in refluxing 1,2-dichloroethane. Azaspirotrienones can be synthesized from p-hydroxyphenethyl or 3-(p-hydroxyphenyl)propyl ketone oximes by applying the above method. Thus prepared azaspirotrienones are converted to quinolines by acid treatment.

Reaction of a Possible Iminoketene Precursor with 6,7-Dialkoxy-1,3-dialkyl-3,4-dihydroisoquinolines

Reaction of 6,7-dialkoxy-1-alkyl-3,4-dihydro-3-methylisoquinolines (10 - 12) with sulphinamide anhydride (13) yields 2,3-dialkoxy-5,6,7,8-tetrahydro-6-methyl-8-oxoisoquinolinoquinazolines (14 and 19) and 2,3-dialkoxy-13a-alkyl-5,6,7,8,13,13a-hexahydro-6-methyl-8-oxoisoquinolinoquinazolines (15 - 17 and 20).Of the two possible geometrical isomers of the latter class of compounds, the cis-isomer predominates and the trans-isomer is found to be labile towards aerial oxidation.No evidence for the generation of iminoketene (21) is obtained in the reaction of sulphinamide anhydride (13) with various 3,4-dihydroisoquinoline derivatives.