14089-52-2

Basic information

• Product Name: N-Ethyl-1-[(1,3-benzodioxole-5-yl)methyl]ethanamine
• Synonyms: N-Ethyl-1-[(1,3-benzodioxole-5-yl)methyl]ethanamine;N-Ethylmethylenedioxyamphetamine;N-Ethyl-α-methyl-1,3-benzodioxole-5-ethanamine;N-Ethyl-α-methyl-3,4-(methylenedioxy)phenethylamine;N-Ethyl-alpha-methyl-1,3-benzodioxole-5-ethanamine
• CAS NO: 14089-52-2
• Molecular Formula: C₁₂H₁₇NO₂
• Molecular Weight: 207.2689
• Mol File: 14089-52-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 284.578°C at 760 mmHg
• Flash Point: 116.566°C
• Appearance: /
• Density: 1.079g/cm3
• Vapor Pressure: 0.003mmHg at 25°C
• Refractive Index: 1.531
• CAS DataBase Reference: N-Ethyl-1-[(1,3-benzodioxole-5-yl)methyl]ethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-Ethyl-1-[(1,3-benzodioxole-5-yl)methyl]ethanamine(14089-52-2)
• EPA Substance Registry System: N-Ethyl-1-[(1,3-benzodioxole-5-yl)methyl]ethanamine(14089-52-2)

Safety Data

• Hazardous Substances Data: 14089-52-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C12H17NO2/c1-3-13-9(2)6-10-4-5-11-8-14-15-12(11)7-10/h4-5,7,9,13H,3,6,8H2,1-2H3

Upstream product

• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 
• 557-66-4 ethanamine hydrochloride 
• 75-04-7 ethylamine 
• 36209-71-9 N-[1-methyl-2-(3,4-methylenedioxyphenyl)ethyl]acetamide 
• 5438-41-5 5-(2-nitroprop-1-enyl)benzo[d][1,3]dioxole 
• 4764-17-4 3,4-methylenedioxyamphetamine 

Downstream Products

• 4764-17-4 3,4-methylenedioxyamphetamine 

Relevant articles and documents

Centrally active N-substituted analogs of 3,4-methylenedioxyphenylisopropylamine (3,4-methylenedioxyamphetamine)

The known central nervous system activity of 3,4-methylenedioxyphenylisopropylamine and its N-methyl homolog prompted the synthesis of a series of analogs with substituents on the nitrogen atom. Most of these analogs (R = alkyl, alkenyl, hydroxy, alkoxy, and alkoxyalkyl) were prepared by the reductive alkylation of 3,4-methylenedioxyphenylacetone with the appropriate amine and sodium cyanoborohydride. Hindered isomers were synthesized indirectly. Measurements of their pharmacological activity in several animal assays and in human subjects indicated that the central activity decreased with the increasing bulk of the N-substituent.