87095-03-2

Basic information

• Product Name: 5-(2-nitropropyl)-1,3-benzodioxole
• CAS NO: 87095-03-2
• Molecular Formula: C₁₀H₁₁NO₄
• Molecular Weight: 209.1986
• Mol File: 87095-03-2.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 340.3°C at 760 mmHg
• Flash Point: 160.4°C
• Density: 1.282g/cm³
• Vapor Pressure: 8.68E-05mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: 5-(2-nitropropyl)-1,3-benzodioxole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-nitropropyl)-1,3-benzodioxole(87095-03-2)
• EPA Substance Registry System: 5-(2-nitropropyl)-1,3-benzodioxole(87095-03-2)

Safety Data

• Hazardous Substances Data: 87095-03-2(Hazardous Substances Data)

Upstream product

• 5438-41-5 5-(2-nitroprop-1-enyl)benzo[d][1,3]dioxole 
• 120-57-0 piperonal 
• 5438-41-5 2-nitro-1-(3,4-methylenedioxyphenyl)-1-propene 

Downstream Products

• 36209-71-9 N-[1-methyl-2-(3,4-methylenedioxyphenyl)ethyl]acetamide 
• 4676-39-5 1-(1,3-benzodioxol-5-yl)-2-propanone 
• 4421-09-4 piperonylonitrile 
• 4764-17-4 3,4-methylenedioxyamphetamine 

Relevant articles and documents

Copper-Catalyzed Propargylation of Nitroalkanes

Using a commercially available, inexpensive, and abundant copper catalyst system, an efficient α-functionalization of nitroalkanes with propargyl bromides is now established. This mild and robust method is highly functional group tolerant and provides straightforward access to complex secondary and tertiary homopropargylic nitroalkanes. Moreover, the utility of these α-propargylated nitroalkanes is demonstrated through downstream functionalization to biologically relevant, five-membered N-heterocycles such as pyrroles and 2-pyrrolines.