36209-85-5

Upstream product

• 23819-54-7 N-tert butyl-N-(4-tert butylphenyl)hydroxylamine 
• 616-38-6 carbonic acid dimethyl ester 
• 446821-83-6 (2-bromo-4-tert-butyl-phenyl)-tert-butylmine 
• 3972-65-4 1-bromo-4-tert-butylbenzene 
• 75-64-9 tert-butylamine 
• 3972-56-3 4-(tert-butyl)chlorobenzene 
• 78-83-1 2-methyl-propan-1-ol 
• 142-04-1 aniline hydrochloride 

Relevant academic research and scientific papers

(DiMeIHeptCl)Pd: A Low-Load Catalyst for Solvent-Free (Melt) Amination

(DiMeIHeptCl)Pd, a hyper-branched N-aryl Pd NHC catalyst, has been shown to be efficient at performing amine arylation reactions in solvent-free ("melt") conditions. The highly lipophilic environment of the alkyl chains flanking the Pd center serves as lubricant to allow the complex to navigate through the paste-like environment of these mixtures. The protocol can be used on a multi-gram scale to make a variety of aniline derivatives, including substrates containing alcohol moieties.

Hetero-Cope rearrangement for the synthesis of potassium 5-tert-butyl-2-(tert-butyl-aminoxy)-benzoate, a highly water-soluble stable free radical

The hetero-Cope rearrangement of 4-tert-butyl-phenyl-tert-butylhydroxylamine provides an easy access to the corresponding ortho-bromoaniline, converted to the new highly water-soluble nitroxide, potassium 5-tert-butyl-2-(tert-butyl-aminoxy)-benzoate. The parent carboxylic acid was found to be very persistent in water at pH 1.