36236-72-3Relevant academic research and scientific papers
Synthesis of 1,3-dioxolanes from substituted benzaldehydes of the vanillin series
Dikusar, E. A.,Potkin, V. I.,Zvereva, T. D.,Zhukovskaya, N. A.,Zubenko, Yu. S.,Kletskov, A. V.,Zolotar, R. M.,Chepik, O. P.
, p. 1537 - 1539,3 (2020/09/16)
Abstract-Condensation of substituted benzaldehydes of the vanillin series with propane-1,2-diol and 3- chloropropane-1,2-diol in boiling benzene in the presence of FIBAN K-1 sulfonated cation exchanger as catalyst gave the corresponding substituted 1,3-di
The synthesis and spectral characterization of complexes of Co(II), Ni(II), Cu(II) and Zn(II) with a new 1,3-dioxolane derivatives of unsymmetrical vic-dioximes
Canpolat,Kaya
, p. 807 - 815 (2007/10/03)
Two new vic-dioxime ligands containing 1,3-dioxolane ring and ethylenediamine, N′-hydroxy-2-(hydroxyimino)-N-(2- {[(2-phenyl-1,3- dioxolan-4-yl)methyl]amino}ethyl)ethanimidamide (L1H2), N′-hydroxy-2-(hydroxyimino)-N-(2-{[(2-methyl-2-
1,3-Dioxolane-based ligands as a novel class of α1-adrenoceptor antagonists
Brasili, Livio,Sorbi, Claudia,Franchini, Silvia,Manicardi, Massimo,Angeli, Piero,Marucci, Gabriella,Leonardi, Amedeo,Poggesi, Elena
, p. 1504 - 1511 (2007/10/03)
1,3-Dioxolane-based compounds (2-14) were synthesized, and the pharmacological profiles at α1-adrenoceptor subtypes were assessed by functional experiments in isolated rat vas deferens (α1A), spleen (α1B), and aorta (α1D). Compound 9, with a pA2 of 7.53, 7.36, and 8.65 at α1A, α1B, and α1D, respectively, is the most potent antagonist of the series, while compound 10 with a pA2 of 8.37 at α1D subtype and selectivity ratios of 162 (α1D/α1A) and 324 (α1D/α1B) is the most selective. Binding assays in CHO cell membranes expressing human cloned α1-adrenoceptor subtypes confirm the pharmacological profiles derived from functional experiments, although the selectivity values are somewhat lower. Therefore, it is concluded that 1,3-dioxolane-based ligands are a new class of α1-adrenoceptor antagonists.
Chemistry of dioxacycloalkanes: VII. Synthesis and properties of substituted 1,3-dioxolanes derived from carbocyclic aldehydes
Kerimov
, p. 136 - 140 (2007/10/03)
Reactions of 3-cyclohexenecarbaldehyde, 6-methyl-3-cyclohexenecarbaldehyde, bicyclo[2.2.1]-hept-5-ene-endo-2-carbaldehyde, and benzaldehyde with 1,2-propanediol and 3-chloro-1,2-propanediol gave the corresponding 2,4-substituted 1,3-dioxolanes. Their reactions with peroxyacetic acid, bromine, dichlorocarbene, and nucleophiles were studied. The effect of the substituents in the diol and aldehyde on their relative reactivity is discussed.
TETRAFLUOROBORIC ACID - A NEW CATALYST FOR THE SYNTHESIS OF 1,3-DIOXOLANES. PREPARATION OF HYDROXYACETONE
Gevorkyan, A. A.,Kazaryan, P. I.,Avakyan, O. V.,Vardanyan, R. A.
, p. 27 - 30 (2007/10/02)
It is established that tetrafluoroboric acid (HBF4) is an effective catalyst for halogen substitution reactions of oxiranes (epichlorohydrin and 1-bromo-3-methyl-2,3-epoxybutane) with aldehydes and ketones, forming 1,3-dioxolanes in high yield.
N-Benzyl Pyridinium Salta as New Useful Catalysts for Transformation of Epoxides to Cyclic Acetals, Orthoesters, and Orthocarbonates
Lee, Sang-Bong,Takata, Toshikazu,Endo, Takeshi
, p. 2019 - 2022 (2007/10/02)
In the presence of catalytic amount of N-(4-methoxybenzyl)-2-cyanopyridinium hexafluoroantimonate, the reaction of a few epoxides with aldehydes, ketones, lactones, and carbonates efficiently afforded corresponding cyclic acetals, orthoesters, and orthocarbonates under mild conditions.
Reaction of 1,3-dioxolans with Iodine Monochloride: the Scope and Mechanism of Formation of 1,3-dioxolan-2-ylium Dichloroiodates(I)
Goosen, Andre,McCleland, Cedric W.
, p. 977 - 983 (2007/10/02)
Treatment of a series of 2-substituted-4,4,5,5-tetramethyl-1,3-dioxolanes with iodine monochloride afforded the appropriate 2-substituted-4,4,5,5-tetramethyl-1,3-dioxolan-2-ylium dichloroiodate(I) salts in excellent yields.In contrast to the stable 2-aryl-substituted salts, the 2-alkyl and unsubstituted derivatives were relatively labile.While 2-phenyl-1,3-dioxolan and 2-phenyl-1,3-dioxan afforded low yields of unstable salts,crystalline products could not be isolated from 4,5-disubstituted dioxolans.The reaction was inhibited by electron-withdrawing 4- and 5-substituents.From a study of the effects of photolysis and added iodine, the mechanism is proposed to involve a hydride ion transfer.Possible reasons for the formation of dichloroiodate(I) rather then monohalide salts, are outlined.The stability of the 2-aryl-substituted salts is dicussed in terms of charge distribution in the cation and possible aryl-anion interactions.
