362605-36-5

Upstream product

• 532-32-1 sodium benzoate 
• 362605-47-8 phosphoric acid 4-{(3S,4R)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-2-oxo-4-azetidinyl}but-2-ynyl ester diethyl ester 
• 457068-79-0 (3S,4R)-1-(tert-butyldimethylsilyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-(4-hydroxybut-2-ynyl)-2-azetidinone 
• 457068-78-9 (3S,4R)-4-(3,3-dibromoprop-2-enyl)-1-(tert-butyldimethylsilyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-2-azetidinone 
• 74299-77-7 (3S,4R)-1-(tert-butyldimethylsilyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-(2-oxoethyl)-2-azetidinone 
• 151908-05-3 (3S,4R)-1-(tert-butyldimethylsilyl)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-(prop-2-enyl)-2-azetidinone 
• 80433-47-2 (3S,4R)-3-[(1R)-1-(tert-butyldimethylsilyloxy)ethyl]-4-(prop-2-enyl)-2-azetidinone 
• 98-88-4 benzoyl chloride 
• 457068-80-3 (3S,4R)-3-[(1R)-1-tert-butyldimethylsilyloxyethyl]-4-(4-hydroxybut-2-ynyl)-2-azetidinone 

Relevant academic research and scientific papers

Construction of a carbapenam skeleton using palladium-catalyzed cyclization

When a THF solution of β-lactam having propargyl phosphate was warmed in the presence of 5 mol% of Pd2(dba)3·CHCl3, 20 mol% of bidentate ligand and sodium acetate (1.5 equiv.) at 40°C for 22 h, carbapenam was produced in h

Novel synthesis of carbapenam by intramolecular attack of lactam nitrogen toward η1-allenyl and η3-propargylpalladium complex

When a THF solution of β-lactam having propargyl phosphate was warmed in the presence of 5 mol % of Pd2(dba)3·CHCl 3, 20 mol % of a bidentate ligand, and sodium acetate (1.5 equiv) at 40 °C for 22 h, carbapenam was produce