36288-25-2

Usage

Uses

Used in Chemical Synthesis:
Naphthalene, 1-[2-(4-methylphenyl)ethenyl]is used as an intermediate in the synthesis of 3-Methyl Chrysene (M265125), which is a member of the methylated chrysenes (MeChry) family. These compounds are significant constituents of cigarette smoke and have potential carcinogenic properties.
Used in Pharmaceutical Research:
As an aryl hydrocarbon receptor (AhR) agonist, 3-Methyl Chrysene, synthesized using Naphthalene, 1-[2-(4-methylphenyl)ethenyl]as an intermediate, may have potential applications in pharmaceutical research. The agonistic activity towards the AhR can be explored for the development of new drugs targeting various diseases and conditions.
Used in Toxicology Studies:
Due to its role in the synthesis of possibly carcinogenic agents, Naphthalene, 1-[2-(4-methylphenyl)ethenyl]may also be used in toxicology studies to better understand the mechanisms of action and potential health risks associated with exposure to methylated chrysenes and other related compounds found in cigarette smoke.

Upstream product

• 66-77-3 1-naphthaldehyde 
• 1530-37-6 (4-methylbenzyl)triphenylphosphonium chloride 
• 104-82-5 4-Methylbenzyl chloride 
• 826-74-4 1-vinylnaphthalene 
• 2028-84-4 p-methylbenzenediazonium chloride 
• 104-87-0 4-methyl-benzaldehyde 
• 39171-65-8 bromo(naphthalen-1-ylmethyl)triphenyl-λ5-phosphane 
• 90-12-0 1-Methylnaphthalene 
• 3163-27-7 2-(bromomethyl)naphthalene 
• 1032937-95-3 (Z)-1-(1,1,1,3,3,3-hexamethyl-2-(trimethylsilyl)trisilan)-2-(4-methyl)benzene 
• 90-14-2 1-Iodonaphthalene 
• 1032938-14-9 (Z)-2-(4-methylphenyl)-1-[tris(trimethylsilyloxy)silyl]ethene 
• 90-11-9 1-Bromonaphthalene 
• 72735-70-7 2-(4-methylphenyl)ethynylnaphthalene 

Downstream Products

• 101937-30-8 1-(4-Brommethyl-styryl)-naphthalin 
• 108977-33-9 1-<4-(1-Hydroxy-aethyl)-styryl>-naphthalin 
• 102024-90-8 1-<4-Vinyl-styryl>-naphthalin 
• 101936-95-2 1-(4-Formyl-styryl)-naphthalin 

Relevant academic research and scientific papers

Method of photo-induced catalytic selective synthesis of Z- and E-olefins

The invention discloses a method of photo-induced catalytic selective synthesis of Z- and E-olefins. According to the method, a disubstituted acetylene compound is used as a starting raw material, a cheap acid is used as a hydrogen source, a phosphine is

Photo-induced catalytic method for selectively synthesizing cis olefin and trans olefin by using alcohol as hydrogen source

The invention discloses a photo-induced catalytic method for selectively synthesizing a cis olefin and a trans olefin by using alcohol as a hydrogen source. According to the method, a di-substituted acetylene compound is used as an initial raw material, t

Method for catalytic-selectively synthesizing Z- and E-alkene through alcohol supply hydrogen iridium controlled by ligand

The invention discloses a method for catalytic-selectively synthesizing Z- and E-alkene through alcohol supply hydrogen iridium controlled by a ligand. The method comprises the following steps: usinga disubstituted acetylene compound as a starting raw mat

Vinyl tris(trimethylsilyl)silanes: substrates for Hiyama coupling

The oxidative treatment of vinyl tris(trimethylsilyl)silanes with hydrogen peroxide in aqueous sodium hydroxide in tetrahydrofuran generates reactive silanol or siloxane species that undergo Pd-catalyzed cross-couplings with aryl, heterocyclic, and alkenyl halides in the presence of Pd(PPh3)4 and tetrabutylammonium fluoride. Hydrogen peroxide and base are necessary for the coupling to occur while activation of the silanes with fluoride is not required. The conjugated and unconjugated tris(trimethylsilyl)silanes serve as good cross-coupling substrates. The (E)-silanes undergo coupling with retention of stereochemistry while coupling of (Z)-silanes occurred with lower stereoselectivity to produce an E/Z mixture of products.

Triplet Intermediates in Cis-Trans Photoisomerization of 3-Chrysenylethylenes

The effect of substitution of 3-chrysenyl group (Ar) on unsaturated double bonds in their triplet sensitized isomerization was investigated for Ar-CH=CH-R, R = tBu (BC) and Ph (SC) by means of stationary irradiations, laser flash photolyses, and MO calculations.Both olefins undergo mutual isomerization between their cis- and trans-isomers.However, BC has a unique triplet energy surface with two decay funnels at the planar trans (3t*) and twisted (3p*) conformations, which are in equilibrium with each other; 3t* undergoes either unimolecular decay to the ground-state trans isomer or triplet energy transfer to the cis isomer (quantum chain process) and 3p* decays to the ground state to give the cis and trans isomers.Tn 1 absorptions observed for BC and SC are mainly attributed to 3t* and 3p*, respectively, on the basis of semiempirical MO calculations.The populations at 3t* and 3p* are estimated.

1-NAPHTHALENEDIAZONIUM TETRACHLOROCUPRATE - A NEW ARYLATING REAGENT

The conditions were worked out for the catalytic chloronaphthylation of unsaturated compounds by 1-naphthalenediazonium chloride in the Meerwein reaction.The intermediate in this process is 1-naphthalenediazonium tetrachlorocuprate, which is an effective arylating agent.The reaction of this complex salt with unsaturated compounds gave the same chloronaphthylation products but with higher yields.