363619-55-0Relevant academic research and scientific papers
An Efficient Method for the Synthesis of 2,6-Branched Galacto- Oligosaccharides and Its Applications to the Synthesis of Three Tetrasaccharides and a Hexasaccharide Related to the Arabinogalactans (AGs)
Ning, Jun,Yi, Yuetao,Yao, Zhe
, p. 2208 - 2212 (2007/10/03)
An efficient method for the synthesis of 2,6-branched galacto- oligosaccharides has been developed by using 6-O-Ac-2,3,4-tri-O-Bz-α-D- galactopyranosyl trichloroacetimidate, 2,6-di-O-Ac-3,4-di-O-Bz-α-D- galactopyranosyl trichloroacetimidate and 2-O-Ac-3,4,6-tri-O-Bz-α-D- galactopyranosyl trichloroacetimidate as synthons. Three tetrasaccharides and a hexasaccharides related to AGs from plants were readily prepared using this method.
Synthesis of β-D-Galp-(1 →4)-α-D-Manp methanephosphonate, a substrate analogue for the elongating α-D-mannosyl phosphate transferase in the Leishmania
Borodkin, Vladimir S,Ferguson, Michael A.J,Nikolaev, Andrei V
, p. 5305 - 5308 (2007/10/03)
An isosteric C-glycoside phosphono analogue of dec-9-enyl β-D-galactopyranosyl-(1 →4)-α-D-mannopyranosyl phosphate was synthesised and showed high biological activity in the Leishmania MPT assay. A one-step Horner-Emmons/Michael reaction was developed for the stereoselective preparation of α-D-mannosyl methanephosphonate derivatives.
