364049-85-4Relevant academic research and scientific papers
4-CF3-ezetimibe analogs: Design, synthesis, and biological evaluation of cholesterol absorption inhibitions
Liu, Yingle,Chen, Jun-Ling,Wang, Gai-Hong,Sun, Peng,Huang, Heyao,Qing, Feng-Ling
, p. 5541 - 5543 (2013)
On the purpose of looking for better cholesterol absorption inhibitors, several trifluoromethyl substituted ezetimibe analogs 1a-d were designed and synthesized. The key steps in the synthesis of these optically pure trans-4-CF3-β-lactams inclu
One-Pot Synthesis of Trifluoroacetimidoyl Halides
Tamura, Kenji,Mizukami, Hiromichi,Maeda, Kazuhiro,Watanabe, Hisayuki,Uneyama, Kenji
, p. 32 - 35 (2007/10/02)
Trifluoroacetimidoyl chlorides 1 were obtained in 80-90percent yields when a mixture of trifluoroacetic acid and a primary amine was heated in carbon tetrachloride in the presence of triphenylphosphine and triethylamine.The corresponding bromides 2 were o
