3646-61-5

Basic information

• Product Name: 2,8-DICHLORO-6,12-DIPHENYLDIBENZO(B,F)(1,5)DIAZOCINE
• Synonyms: 2,8-DICHLORO-6,12-DIPHENYLDIBENZO(B,F)(1,5)DIAZOCINE;U-10293;2,8-dichloro-6,12-diphenylbenzo[c][1,5]benzodiazocine
• CAS NO: 3646-61-5
• Molecular Formula: C₂₆H₁₆Cl₂N₂
• Molecular Weight: 427.32464
• Mol File: 3646-61-5.mol
• Article Data: 11

Chemical Properties

• Melting Point: 215-217 °C
• Boiling Point: 577.85°C (rough estimate)
• Flash Point: 288.7°C
• Appearance: /
• Density: 1.1615 (rough estimate)
• Vapor Pressure: 9.79E-12mmHg at 25°C
• Refractive Index: 1.6300 (estimate)
• PKA: 1.40±0.40(Predicted)
• CAS DataBase Reference: 2,8-DICHLORO-6,12-DIPHENYLDIBENZO(B,F)(1,5)DIAZOCINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2,8-DICHLORO-6,12-DIPHENYLDIBENZO(B,F)(1,5)DIAZOCINE(3646-61-5)
• EPA Substance Registry System: 2,8-DICHLORO-6,12-DIPHENYLDIBENZO(B,F)(1,5)DIAZOCINE(3646-61-5)

Safety Data

• Hazardous Substances Data: 3646-61-5(Hazardous Substances Data)

Usage

Uses

2,8-Dichloro-6,12-diphenyldibenzo[b,f][1,5]diazocine is synthesized from 2-aminobenzophenones (A603490) with a Lewis acid as condensing agent.

InChI:InChI=1/C26H16Cl2N2/c27-19-11-13-23-21(15-19)25(17-7-3-1-4-8-17)29-24-14-12-20(28)16-22(24)26(30-23)18-9-5-2-6-10-18/h1-16H/b25-21-,26-22-,29-24-,29-25-,30-23-,30-26-

Upstream product

• 719-64-2 5-chloro-3-phenylanthranil 
• 103718-97-4 N-<(2-amino-5-chlorophenyl)phenylmethylene>-1,2-benzenediamine 
• 79-11-8 chloroacetic acid 
• 1122-54-9 methyl (4-pyridyl) ketone 
• 719-59-5 5-chloro-2-aminobenzophenone 
• 350-03-8 methyl-3-pyridylketone 
• 1122-62-9 2-acetylpyridine 
• 18928-48-8 5-Chloro-2-isocyanatobenzoyl chloride 
• 71-43-2 benzene 
• 95-54-5 1,2-diamino-benzene 

Downstream Products

• 10127-72-7 3,8-dichloro-4b,5,9b,10,tetrahydro-4b,9b-diphenylindolo<3,2-b>indole 

Relevant articles and documents

Regioselective intramolecular annulations of ambident β-enamino esters: A diversity-oriented synthesis of nitrogen-containing privileged molecules

Diversity-oriented, regioselective, intramolecular annulation of β-enamino esters is described under solvent-free, calcium-catalysis. 2-aminoaryl ketones and alkyl propiolates undergone a [4+2] annulation to yield substituted quinolines; with an excess of

Synthesis of polysubstituted quinolines via copper(ii)-catalyzed annulation of 2-aminoaryl ketones with alkynoates

Copper triflate catalyzed annulation of 2-aminoaryl ketones with internal alkynes has been developed for the synthesis of polysubstituted quinolines in high yields under solvent-free conditions. Phenyl propiolic acid afforded the 3-unsubstituted quinoline

Simple synthesis of quinolines and dibenzo[b,f][1,5]diazocines under microwave irradiation

Quinolines 3a-f, 5a-f, and dibenzo[b,f][1,5]diazocines 4, 6 were synthesized in the presence of 0.5 equiv. of diphenyl phosphate (DPP) under microwave irradiation. The obtained yield of 6,12-diphenyl-dibenzo[b,f][1,5]diazocine 4 was higher when using anhy