36479-97-7

Basic information

• Product Name: (1,1-dichloro-2-propyl)benzene
• CAS NO: 36479-97-7
• Molecular Weight: 189.084
• Mol File: 36479-97-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1,1-dichloro-2-propyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: (1,1-dichloro-2-propyl)benzene(36479-97-7)
• EPA Substance Registry System: (1,1-dichloro-2-propyl)benzene(36479-97-7)

Safety Data

• Hazardous Substances Data: 36479-97-7(Hazardous Substances Data)

Upstream product

• 156575-60-9 2-(1-phenyl-ethyl)-benzo[1,3,2]dioxaborole 
• 100-42-5 styrene 
• 67-66-3 chloroform 
• 100-41-4 ethylbenzene 
• 3294-58-4 phenyl(bromodichloromethyl)mercury 

Relevant articles and documents

Homologation Strategy for the Generation of 1-Chloroalkyl Radicals from Organoboranes

The generation of 1-bromo and 1-chloroalkyl radicals from organoboranes has been investigated. The direct approach involving the hydroboration of halogenated alkenes is impeded by partial dehalogenation taking place during the hydroboration process. An indirect method involving the generation of B-(1-chloroalkyl)catecholborane by homologation of B-alkylcatecholborane with dichloromethyllithium was developed. A reaction sequence involving a hydroboration reaction, a Matteson homologation, and a radical allylation process has been performed as a one-pot process that takes advantage of three different reactivities of organoboron species. Starting from styrene derivatives, it was possible to prepare B-(1-chloro-2-arylpropyl)catecholboranes that are excellent precursors to 1-chloro-2-arylpropyl radicals. A concise approach for the synthesis of an optically active α-methylene-γ-lactone from p-chlorostyrene has been developed on the basis of a two-step sequence involving an enantioselective hydroboration-homologation-cyclization reaction followed by a hydrolysis-lactonization process. (Chemical Equation Presented).