364793-69-1

Basic information

• Product Name: methyl 2-amino-5-methoxy-4-{[(trifluoromethyl)-sulfonyl]oxy}benzoate
• CAS NO: 364793-69-1
• Molecular Weight: 329.254
• Mol File: 364793-69-1.mol

Chemical Properties

• CAS DataBase Reference: methyl 2-amino-5-methoxy-4-{[(trifluoromethyl)-sulfonyl]oxy}benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-amino-5-methoxy-4-{[(trifluoromethyl)-sulfonyl]oxy}benzoate(364793-69-1)
• EPA Substance Registry System: methyl 2-amino-5-methoxy-4-{[(trifluoromethyl)-sulfonyl]oxy}benzoate(364793-69-1)

Safety Data

• Hazardous Substances Data: 364793-69-1(Hazardous Substances Data)

Upstream product

• 27883-60-9 4-hydroxy-5-methoxy-2-nitrobenzoic acid methyl ester 
• 56441-97-5 methyl 4-(benzyloxy)-3-methoxybenzoate 
• 61032-41-5 methyl 4-(benzyloxy)-5-methoxy-2-nitrobenzoate 
• 3943-74-6 4-hydroxy-3-methoxybenzoic acid methyl ester 
• 364793-68-0 5-methoxy-2-nitro-4-trifluoromethanesulfonyloxy-benzoic acid methyl ester 

Downstream Products

• 364793-70-4 methyl 2-{[(E)-(dimethylamino) methylidene]amino}-5-methoxy-4 {[(trifluoromethyl) sulfonyl]oxy}benzoate 
• 364793-73-7 3-cyano-4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxyquinolin-7-yl trifluoromethanesulfonate 
• 364793-72-6 (4-chloro-3-cyano-6-methoxy-7-quinolyl)trifluoromethanesulfonate 
• 364793-71-5 3-cyano-6-methoxy-4-oxo-1,4-dihydro-7-quinolinyl trifluoromethanesulfonate 

Relevant articles and documents

3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors

This invention provides compounds of Formula (I), having the structure where T, Z, X, A, R1, R2a, R2b, R2c, R3, R4, and n are defined herein, or a pharmaceutically acceptable salt thereof which are useful as antineoplastic agents and in the treatment of osteoporosis and polycystic kidney disease.

Substituted 4-anilino-7-phenyl-3-quinolinecarbonitriles as Src kinase inhibitors

A series of substituted 4-anilino-7-phenyl-3-quinolinecarbonitriles has been prepared as Src kinase inhibitors. Optimal activity is observed with compounds that have basic amines attached via the para position of the 7-phenyl ring, and a hydrogen atom at the C-6 position. The best compounds are low nanomolar inhibitors of Src kinase, and have potent activity against Src-transformed fibroblast cells.