365565-90-8Relevant articles and documents
Novel human histamine H(3) receptor antagonists.
Shah, Chandra,McAtee, Laura,Breitenbucher, J Guy,Rudolph, Dale,Li, Xiaobing,Lovenberg, Timothy W,Mazur, Curt,Wilson, Sandy J,Carruthers, Nicholas I
, p. 3309 - 3312 (2007/10/03)
High throughput screening, using the recombinant human H(3) receptor, was used to identify novel histamine H(3) receptor antagonists. Evaluation of the lead compounds ultimately afforded potent, selective, orally bioavailable compounds (e.g., 38) with fav