3658-93-3

Basic information

• Product Name: HEXALDEHYDE DIETHYL ACETAL
• Synonyms: 1,1-diethoxy-hexan;1,1-diethoxy-Hexane;HEXANAL DIETHYL ACETAL;HEXANAL:DIETHYL ACETAL;HEXALDEHYDE DIETHYL ACETAL;Hexanaldiacetal;Hexane, 1,1-diethoxy-;HEXYLALDEHYDEDIETHYLACETAL
• CAS NO: 3658-93-3
• Molecular Formula: C₁₀H₂₂O₂
• Molecular Weight: 174.28
• EINECS: 222-911-4
• Mol File: 3658-93-3.mol

Chemical Properties

• Boiling Point: 90°C/30mmHg(lit.)
• Flash Point: 43.8°C
• Appearance: /
• Density: 0.843g/cm³
• Vapor Pressure: 0.804mmHg at 25°C
• Refractive Index: 1.4060-1.4100
• CAS DataBase Reference: HEXALDEHYDE DIETHYL ACETAL(CAS DataBase Reference)
• NIST Chemistry Reference: HEXALDEHYDE DIETHYL ACETAL(3658-93-3)
• EPA Substance Registry System: HEXALDEHYDE DIETHYL ACETAL(3658-93-3)

Safety Data

• RIDADR: 1993
• HazardClass: 3
• PackingGroup: III
• Hazardous Substances Data: 3658-93-3(Hazardous Substances Data)

Usage

Uses

Used in the Food Industry:
Hexaldehyde diethyl acetal is used as a flavoring agent for its fruity, green apple-like aroma, enhancing the taste and smell of various food and beverage products.
Used in the Perfumery and Fragrance Industry:
Hexaldehyde diethyl acetal is employed as a component in the manufacturing of perfumes and fragrances, contributing to the creation of complex and appealing scents.
Used in the Chemical Industry:
Hexaldehyde diethyl acetal serves as a raw material in the production of other chemical compounds, showcasing its versatility in different applications.

InChI:InChI=1/C10H22O2/c1-4-7-8-9-10(11-5-2)12-6-3/h10H,4-9H2,1-3H3

Upstream product

• 64-17-5 ethanol 
• 66-25-1 hexanal 
• 142-61-0 Hexanoyl chloride 
• 122-51-0 orthoformic acid triethyl ester 
• 52358-05-1 2-hydroxyheptanoic acid 
• 592-41-6 1-hexene 
• 1561-39-3 1,1-dichloro-3,3-diethoxy-propene 
• 62761-29-9 3-chloropropargyl aldehyde diethyl acetal 
• 64769-00-2 2-acetoxy-heptanoic acid 
• 3777-62-6 1,1-diethoxy-hexa-2,4-diyne 

Downstream Products

• 14092-07-0 1-ethoxy-hex-1-ene 
• 54305-98-5 1,1,3-triethoxy-octane 
• 66-25-1 hexanal 
• 21037-62-7 2-diethoxymethyl-1,1-diethoxyhexane 
• 54306-01-3 1,1-diethoxy-oct-2-ene 
• 2363-88-4 deca-2,4-dienal 
• 2548-87-0 2-octen-1-al 

Relevant articles and documents

One-pot Synthesis of Acetals by Tandem Hydroformylation-acetalization of Olefins Using Heterogeneous Supported Catalysts

Abstract: A green route for one?pot synthesis of acetals by tandem hydroformylation?acetalization of olefins using supported Rh?based?catalysts was developed. Experimental results demonstrated that suitable Rh loading (1 wt%) with appropriate reaction temperature (120?°C) and reaction time (8?h) were favorable for the formation of acetals, and a high acetals selectivity of 94.6% was achieved. More importantly, the selectivity to valuable linear products was enhanced in this tandem catalysis. Based on the catalytic mechanism study, highly dispersed RhOx nanoparticles and abundant acid sites on the supports were responsible for the hydroformylation and acetalization, respectively. Graphical abstract: One-pot synthesis of acetals directly from olefins with high selectivity was achieved over heterogeneous bifunctional catalysts via tandem hydroformylation-acetalization. [Figure not available: see fulltext.]

Hexameric resorcinarene capsule is a bronsted acid: Investigation and application to synthesis and catalysis

Molecular capsules have attracted interest as simple enzyme mimetics and several examples of catalytic transformations in water-soluble metal-ligand based systems have been reported. This is not the case for hydrogen-bond based molecular capsules, which in contrast can be employed in organic solvents. We describe herein our investigations of such a system: The resorcin[4]arene hexamer is one of the largest hydrogen bond-based self-assembled capsules and has been studied intensively due to its ready availability. We present evidence that the capsule acts as a reasonably strong Bronsted acid (pK a approximately 5.5-6). This finding explains the capsule's high affinity toward tertiary amines that are protonated and therefore encounter cation-π interactions inside the cavity. We were able to translate this finding into a first synthetic application: A highly substrate-selective Wittig reaction. We also report that this property renders the capsule an efficient enzyme-like catalyst for substrate selective diethyl acetal hydrolysis.

Characterization of aroma compounds of Chinese "Wuliangye" and "Jiannanchun" liquors by aroma extract dilution analysis

Aroma compounds in Chinese "Wuliangye" liquor were identified by gas chromatography-olfactometry (GC-O) after fractionation. A total of 132 odorants were detected by GC-O in Wuliangye liquor on DB-wax and DB-5 columns. Of these, 126 aromas were identified by GC-mass spectrometry (MS). Aroma extract dilution analysis (AEDA) was further employed to identify the most important aroma compounds in "Wuliangye" and "Jiannanchun" liquors. The results showed that esters could be the most important class, especially ethyl esters. Various alcohols, aldehydes, acetals, alkylpyrazines, furan derivatives, lactones, and sulfur-containing and phenolic compounds were also found to be important. On the basis of flavor dilution (FD) values, the most important aroma compounds in Wuliangye and Jiannanchun liquors could be ethyl butanoate, ethyl pentanoate, ethyl hexanoate, ethyl octanoate, butyl hexanoate, ethyl 3-methylbutanoate, hexanoic acid, and 1,1-diethoxy-3-methylbutane (FD ≥ 1024). These compounds contributed to fruity, floral, and apple- and pineapple-like aromas with the exception of hexanoic acid, which imparts a sweaty note. Several pyrazines, including 2,5-dimethyl-3-ethylpyrazine, 2-ethyl-6-methylpyrazine, 2,6-dimethylpyrazine, 2,3,5-tri-methylpyrazine, and 3,5-dimethyl-2-pentylpyrazine, were identified in these two liquors. Although further quantitative analysis is required, it seems that most of these pyrazine compounds had higher FD values in Wuliangye than in Jiannanchun liquor, thus imparting stronger nutty, baked, and roasted notes in Wuliangye liquor.

Ruthenium(III) chloride-catalyzed chemoselective synthesis of acetals from aldehydes

A mild and chemoselective acetalization procedure for the protection of various aldehydes in the presence of ketones is described.

Method for producing enol ethers

Enol ethers of the formula I where R1is an aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic radical which may carry further substituents which do not react with acetylenes or allenes, and the radicals R, independently of one another, are hydrogen or aliphatic, cycloaliphatic, araliphatic, aromatic or heterocyclic radicals, which may be bonded to one another to form a ring, and m is 0 or 1, are prepared by reacting an acetal or ketal of the formula II with an acetylene or allene of the formula III or IV where R and R1have the abovementioned meanings, in the gas phase at elevated temperatures in the presence of a zinc- or cadmium- and silicon- and oxygen-containing heterogeneous catalyst.

Method of preparing acetal or ketal

A method of preparing an acetal or ketal from a corresponding aldehyde or ketone is disclosed. A hydrous oxide of an element of Group IV of the Periodic Table is used as a catalyst, and the aldehyde or ketone is caused to react with an alcohol. The hydrous oxide can be obtained by partially dehydrating a hydroxide of the corresponding element. The method does not require an acid catalyst and is applicable to a carbonyl compound which is not stable in acids.

The Catalytic Reduction of Aldehydes and Ketones with 2-Propanol over Hydrous Zirconium Oxide

Reduction of aldehydes with 2-propanol proceeded efficiently by catalysis with hydrous zirconium oxide to give the corresponding alcohols.Most ketones also were reduced efficiently, but conjugated or sterically hindered ketones resisted the reduction.The reduction was carried out with primary, secondary, or tertiary alcohols, and only secondary alcohols served as hydrogen donors.Kinetic experiments have indicated that the reaction rate is first-order dependence on each of the concentrations of the carbonyl compound, 2-propanol, and the catalyst.An observation of the primary isotope effect has suggested that a step of hydride transfer from absorbed 2-propanol to absorbed carbonyl compound constitutes the rate-determining step for the reduction.