36586-44-4Relevant academic research and scientific papers
A facile synthesis of acylhydrazines from acylbenzotriazoles
Wang, Xiaoxia,Yu, Hongping,Xu, Peifang,Zheng, Renwei
, p. 595 - 597 (2007/10/03)
Acylbenzotriazoles were found to react with substituted hydrazines and aqueous hydrazine under very mild conditions, thus affording a facile synthesis of three types of acylhydrazines in moderate to excellent yields.
A rapid and convenient method for preparing acylhydrazines from acyldiazenes
Li, Jian-Ping,Yu, Shu-Qiang,Qu, Gui-Rong,Wang, Yu-Lu
, p. 835 - 837 (2007/10/03)
The synthesis of acylhydrazines by using hydrazine hydrate as the reductant to hydrogenate acyldiazenes is reported. Twelve acylhydrazines have been synthesized from acyldiazenes in excellent yields under mild conditions. This method is rapid, convenient, and efficient.
Rapid and convenient synthesis of acylhydrazines from acyldiazenes
Li, Jian-Ping,Yu, Shu-Qiang,Qu, Gui-Rong,Wang, Yu-Lu
, p. 41 - 42 (2007/10/03)
The synthesis of acylhydrazines by using phenylhydrazine as the reductant to hydrogenate acyldiazenes is reported.
1,3-Diarylcycloalkanopyrazoles and diphenyl hydrazides as selective inhibitors of cyclooxygenase-2
Sui, Zhihua,Guan, Jihua,Ferro, Michael P.,McCoy, Kathy,Wachter, Michael P.,Murray, William V.,Singer, Monica,Steber, Michele,Ritchie, Dave M.,Argentieri, Dennis C.
, p. 601 - 604 (2007/10/03)
Novel 1,3-diarylcycloalkanopyrazoles 1, and diphenyl hydrazides 2 were identified as selective inhibitors of cyclooxygenase-2. The 1,3-diaryl substitution pattern of the pyrazole ring in 1 differentiates these compounds from most of the known selective COX-2 inhibitors that contain two aryl rings at the adjacent positions on a heterocyclic or a phenyl ring. Similarly, the two phenyl rings in 2 are also separated by three atoms. SAR of both phenyl rings in 1 and 2, and the aliphatic ring in 1 will be discussed. (C) 2000 Elsevier Science Ltd. All rights reserved.
