4231-69-0

Basic information

• Product Name: 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole
• Synonyms: 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole
• CAS NO: 4231-69-0
• Molecular Weight: 253.26
• Mol File: 4231-69-0.mol
• Article Data: 24

Chemical Properties

• CAS DataBase Reference: 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole(4231-69-0)
• EPA Substance Registry System: 1-(4-methoxybenzoyl)-1H-1,2,3-benzotriazole(4231-69-0)

Safety Data

• Hazardous Substances Data: 4231-69-0(Hazardous Substances Data)

Upstream product

• 95-14-7 1,2,3-Benzotriazole 
• 100-07-2 4-methoxy-benzoyl chloride 
• 201230-82-2 carbon monoxide 
• 100-09-4 4-methoxybenzoic acid 
• 37073-15-7 1-(methanesulfonyl)-1H-1,2,3-benzotriazole 
• 103517-57-3 N₁-(4-methoxybenzoyl)-1,2-benzenediamine 
• 203070-03-5 1-[(4-Methoxy-phenyl)-phenylselanyl-methyl]-1H-benzotriazole 
• 824-94-2 p-methoxybenzyl chloride 
• 133349-85-6 1-(4''-methoxybenzyl)-1H-benzo[d][1.2.3]triazole 
• 203070-26-2 1-[(4-Methoxy-phenyl)-bis-phenylselanyl-methyl]-1H-benzotriazole 

Downstream Products

• 4160-63-8 2-(4-methoxybenzoyl)thiophene 
• 21493-89-0 (4-methoxyphenyl)(5-methyl-2-furyl)methanone 
• 53416-46-9 2-(4-methoxyphenyl)-4,4-dimethyl-2-oxazoline 
• 68659-45-0 4-methoxy-benzoic acid 1-cyano-1-methyl-ethyl ester 
• 2620-81-7 2-(4-methoxyphenyl)-1H-benzimidazole 
• 22711-21-3 4-methoxybenzil 
• 54945-17-4 1-(4-chlorophenyl)-2-(4-methoxyphenyl)-ethane-1,2-dione 
• 33425-19-3 1-(4-methoxyphenyl)-2-(4-methylphenyl)ethane-1,2-dione 
• 1226-42-2 1,2-bis(4-methoxyphenyl)-1,2-ethanedione 
• 444148-38-3 5-(4-methoxyphenyl)-3-(3,4,5-trimethoxyphenyl)-1,2,4-oxadiazole 
• 753488-89-0 5-methoxy-1-(4-methoxybenzoyl)-1H-indole 
• 52498-87-0 (1H-indol-1-yl)(4-methoxyphenyl)methanone 
• 876893-18-4 N-[(1H-1,2,3-benzotriazol-1-yl)(4-methoxyphenyl)methylidene]-N-benzylamine 
• 2881-83-6 ethyl 4-methoxybenzoylacetate 

Relevant articles and documents

Nickel-Catalyzed Reductive Cross-Coupling of N-Acyl and N-Sulfonyl Benzotriazoles with Diverse Nitro Compounds: Rapid Access to Amides and Sulfonamides

Herein we report a Ni-catalyzed reductive transamidation of conveniently available N-acyl benzotriazoles with alkyl, alkenyl, and aryl nitro compounds, which afforded various amides with good yields and a broad substrate scope. The same catalytic reaction conditions were also applicable for N-sulfonyl benzotriazoles, which could undergo smooth reductive coupling with nitroarenes and nitroalkanes to afford the corresponding sulfonamides.

N-Acylbenzotriazole: convenient approach for protecting group-free monoacylation of symmetric diamines

Abstract: An efficient green route for monoacylation of aromatic diamines, namely o-phenylenediamine and p-phenylenediamine and aliphatic diamines ethylenediamine and piperazine using N-acylbenzotriazoles (NABs) in n-butanol was developed. The new protocol does not require prior selective protection of the diamine and comprises simple conditions, short reaction times, an easy work up as well as high isolated yields (69–94%). Moreover, the method described herein enable stepwise acylation of aliphatic diamines such as ethylenediamine and piperazine with two different N-acylbenzotriazoles affording unsymmetrical substituted diamines that can be used for construction of pharmaceutically important targets such as drugs, foldamers, and drug conjugates. Graphic abstract: [Figure not available: see fulltext.]

Tert -Butyl nitrite mediated nitrogen transfer reactions: Synthesis of benzotriazoles and azides at room temperature

A conversion of o-phenylenediamines into benzotriazoles was achieved at room temperature using tert-butyl nitrite. The optimized conditions are also well suited for the transformation of sulfonyl and acyl hydrazines into corresponding azides. This protocol does not require any catalyst or acidic medium. The desired products were obtained in excellent yields in a short span of time.