3663-46-5

Basic information

• Product Name: (2,2,5-TRIMETHYL-[1,3]DIOXAN-5-YL)METHANOL
• Synonyms: (2,2,5-TRIMETHYL-[1,3]DIOXAN-5-YL)METHANOL;2,2-DIMETHYL-1,3-DIOXANE-5-METHYL-5-METHANOL;(2,2,5-TRIMETHYL)-(1,3)DIOXAN-5-YL)METH&;5-hydroxymethyl-2,2,5-trimethyl-1,3-dioxane;(2,2,5-Trimethyl-[1,3]dioxan-5-yl)methanol, 2,2,5-Trimethyl-1,3-dioxane-5-methanol;5-Hydroxymethyl-2,2,5-trimethyl-1,3-dioxane 96%
• CAS NO: 3663-46-5
• Molecular Formula: C₈H₁₆O₃
• Molecular Weight: 160.21
• Product Categories: Aromatic alcohols and diols
• Mol File: 3663-46-5.mol
• Article Data: 29

Chemical Properties

• Boiling Point: 75 °C(lit.)
• Flash Point: 215 °F
• Appearance: /
• Density: 1.062 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.038mmHg at 25°C
• Refractive Index: n20/D 1.4520(lit.)
• CAS DataBase Reference: (2,2,5-TRIMETHYL-[1,3]DIOXAN-5-YL)METHANOL(CAS DataBase Reference)
• NIST Chemistry Reference: (2,2,5-TRIMETHYL-[1,3]DIOXAN-5-YL)METHANOL(3663-46-5)
• EPA Substance Registry System: (2,2,5-TRIMETHYL-[1,3]DIOXAN-5-YL)METHANOL(3663-46-5)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 3663-46-5(Hazardous Substances Data)

Usage

General Description

(2,2,5-Trimethyl-[1,3]dioxan-5-yl)methanol is a chemical compound with the molecular formula C8H16O2. It is also known as menthofuran, and it is commonly used as a flavoring agent in the food and beverage industry, particularly in the production of mint-flavored products. (2,2,5-TRIMETHYL-[1,3]DIOXAN-5-YL)METHANOL is a colorless liquid with a strong, minty odor and taste. It is synthesized from natural sources and is considered safe for consumption in moderate amounts. Additionally, it is used in the production of perfumes and other cosmetic products due to its pleasant aroma. However, it should be handled with care and in accordance with safety guidelines due to its flammable and potentially hazardous properties.

InChI:InChI=1/C8H16O3/c1-7(2)10-5-8(3,4-9)6-11-7/h9H,4-6H2,1-3H3

Upstream product

• 77-85-0 2-(hydroxymethyl)-2-methylpropane-1,3-diol 
• 77-76-9 2,2-dimethoxy-propane 
• 67-64-1 acetone 
• 100-02-7 4-nitro-phenol 
• 151134-14-4 2-(2-chloro-5-methyl-1,3,2-dioxaphosphorinan-5-yl2-sulfide)methoxyacetic acid, methyl ester 

Downstream Products

• 4270-73-9 2-methyl-2-<(benzyloxy)methyl>-1,3-propanediol 
• 137378-16-6 5-benzyloxymethyl-5-methyl-3,7-dioxanonane-1,9-diol 
• 137378-17-7 5-benzyloxymethyl-5-methyl-1,9-ditoluene-p-sulfonato-3,7-dioxanonane 
• 136466-33-6 6-benzyloxymethyl-6-methyl-1,4,8,11-tetraoxacyclotetradecane 
• 147067-16-1 6-toluene-p-sulfonyloxymethyl-6-methyl-1,4,8,11-tetraoxacyclotetradecane 
• 146630-92-4 6,13-bis(benzyloxymethyl)-6,13-dimethyl-1,4,8,11-tetraoxacyclotetradecane 
• 171416-30-1 diethyl 5-benzyloxymethyl-5-methyl-3,7-dioxanonanedioate 
• 171416-22-1 trans-6,13-ditoluene-p-sulfonyloxymethyl-6,13-dimethyl-1,4,8,11-tetraoxacyclotetradecane 
• 1067-09-0 1,3-dichloro-2-(chloromethyl)-2-methylpropane 
• 21398-89-0 2-methoxymethyl-2-methyl-1,3-propanediol 
• 126369-99-1 1-methoxy-2,2-bis(p-toluenesulfonyloxymethyl)propane 
• 108366-82-1 2-(2,5-dioxahexyl)-2-methyl-1,3-propanediol 
• 108366-83-2 15-Benzyloxymethyl-15-methyl-1,4,7,10,13-pentaoxa-cyclohexadecane 
• 1075753-81-9 3-benzoyl-5-methyl-1-[(2,2,5-trimethyl-1,3-dioxan-5-yl)methyl]pyrimidine-2,4(1H,3H)-dione 

Relevant articles and documents

New organofunctional cyclophosphazene derivatives

The rational design, synthesis and polymerization of the methacrylphosphazenes N3P3Cl5O(CHR)x(CHR′) yOC(O)CMe=CH2 (x=y=1,2, R=R′=H; x=1, R=Me, y=1, R′=H; x=1, R=H, y=1, R′=Me) is reported. Another new type of alkenyloxy derivative is prepared from 5-nonbornene-2-methoxide and N3P3Cl5. The preparation of spirocyclic derivatives with methacrylate or protected hydroxyl groups is reported Various functionalized ferrocene derivatives of the cyclophosphazenes have been prepared with particular attention being paid to the synthesis and electrochemical characterization of the N3P3Cl6-n(NMeCH2C5H 4FeC5H5)n(n=1,2,3,4) series.

Electrospun poly(l -lactide-co -acryloyl carbonate) fiber scaffolds with a mechanically stable crimp structure for ligament tissue engineering

The aim of this study was to prepare a fibrous scaffold that possesses a crimped morphology using a photo-cross-linkable biodegradable copolymer. To obtain the crimped morphology, the polymer was first electrospun onto a rotating wire mandrel to obtain aligned straight fibers. Postprocessing by immersion in aqueous buffer at 37 °C generated a crimplike pattern in the fibers. It was reasoned that cross-linking the fibers following formation of the crimped structure would endow the scaffolds with a recoverable crimp pattern and mechanical properties similar to that of the collagen fibers in the anterior cruciate ligament (ACL). To achieve this aim, a trimethylene carbonate based monomer bearing an acrylate pendant group was synthesized and copolymerized with l-lactide. The copolymer was electrospun and photo-cross-linked yielding fibrous scaffolds possessing a substantial increase in tensile modulus and crimp stability compared to the uncross-linked fibrous scaffolds. The crimp-stabilized scaffolds also showed good cytocompatibility toward 3T3 fibroblasts, which attached and grew along the crimped fibers. These findings suggest that these cross-linked fiber scaffolds may be useful for the generation of cultured ligament tissue.

IMIDAZO[4,5-C]PYRIDINE DERIVATIVES AS TOLL-LIKE RECEPTOR AGONSITS

The present invention relates to imidazo-pyridinyl compounds, or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising such compounds and salts, and to methods of using such compounds, salts and compositions for the treatment of abnormal cell growth, including cancer, in a subject.

POLYMER-PARTICLE LIGHT-CLEAVABLE CARRIER SYSTEMS FOR PHOTODYNAMIC THERAPY

The present invention generally relates to the formation, chemistry and application of biologically active compositions. More particularly, the present invention relates to certain dyes, specifically porphyrin and chlorin derivatives, in combination with