36669-02-0

Basic information

• Synonyms: Dimethyl 3-hydroxyphthalate
• CAS NO: 36669-02-0
• Molecular Formula: C₁₀H₁₀O₅
• Molecular Weight: 210.19
• Mol File: 36669-02-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 54-55 °C
• Boiling Point: 94-96 °C(Press: 0.1 Torr)
• Appearance: /
• Density: 1.284±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• Solubility: Acetonitrile (Slightly), Chloroform (Sparingly), Methanol (Slightly)
• PKA: 8.94±0.10(Predicted)
• CAS DataBase Reference: N/A(CAS DataBase Reference)
• NIST Chemistry Reference: N/A(36669-02-0)
• EPA Substance Registry System: N/A(36669-02-0)

Safety Data

• Hazardous Substances Data: 36669-02-0(Hazardous Substances Data)

Usage

Uses

Dimethyl 3-Hydroxyphthalate is used as a reactant in the synthesis of proteolysis targeting chimeras.

Upstream product

• 18063-93-9 dimethyl 1,4-dimethyl-7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate 
• 85-44-9 phthalic anhydride 
• 684-93-5 1-methyl-1-nitrosourea 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 601-97-8 3-hydroxyphthalic acid 
• 37418-88-5 3-hydroxyphthalic anhydride 
• 75232-81-4 2-Trimethylsilanyl-buta-1,3-dien-1-one 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 108298-54-0 3-Trimethylsilyloxy-dimethyl-phthalate 
• 496-64-0 3-hydroxy-2-pyrone 
• 67609-49-8 3-Trimethylsilanyloxy-cyclohexa-1,4-diene-1,2-dicarboxylic acid dimethyl ester 
• 186581-53-3 diazomethane 
• 16534-14-8 3-hydroxy-phthalic acid-1-methyl ester 

Downstream Products

• 64208-33-9 dimethyl 3-allyloxyphthalate 
• 1061605-96-6 3-(3-bromo-benzyloxy)-phthalic acid dimethyl ester 
• 1061606-07-2 3-(3-methoxy-benzyloxy)-phthalic acid dimethyl ester 
• 1061606-47-0 3-(4-methoxy-benzyloxy)-phthalic acid dimethyl ester 
• 1061605-99-9 3-(3-methyl-benzyloxy)-phthalic acid dimethyl ester 
• 1061605-92-2 3-(3-fluoro-benzyloxy)-phthalic acid dimethyl ester 
• 1061605-82-0 3-(3-chloro-benzyloxy)-phthalic acid dimethyl ester 
• 1061606-36-7 3-(5-chloro-thiophen-2-ylmethoxy)-phthalic acid dimethyl ester 
• 1061606-11-8 3-(benzo[1,3]dioxol-5-ylmethoxy)-phthalic acid dimethyl ester 
• 1061606-42-5 3-(1-naphthalen-2-yl-ethoxy)-phthalic acid dimethyl ester 
• 1061605-88-6 3-(3,5-dichloro-benzyloxy)-phthalic acid dimethyl ester 
• 1061606-24-3 3-(3-chloro-benzo[b]thiophen-2-ylmethoxy)-phthalic acid dimethyl ester 
• 98946-53-3 3-ethoxyphthalic anhydride 
• 50919-55-6 dimethyl 3-ethoxyphthalate 

Relevant articles and documents

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DIELS- ALDER RING-OPENING PROCESS

The invention is directed to a process for the ring-opening of a cycloadduct of formula I obtainable from a reaction of a furanic compound and a diene, said process comprising contacting the cycloadduct with an acidic mixture comprising sulfuric acid and an activating agent to obtain a ring-opened product. The present invention is particularly directed a continuous process.

NOVEL BROMINATED FURANONE DERIVATIVE, METHOD FOR PREPARING SAME, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT

The present invention relates to a novel brominated furanone derivative, a method for preparing the same, and a pharmaceutical composition containing the same as an active ingredient, wherein the novel brominated furanone derivative or a pharmaceutically acceptable 5 salt thereof according to the present invention exhibits a quorum sensing inhibitory activity of bacteria and also can effectively inhibit the formation of biofilm of bacteria, and thus can be used as a pharmaceutical composition containing the same as an active ingredient, thereby having an effect of being useful, 10 for example, for periodontal diseases such as gingivitis and periodontitis, oral diseases, and the like.