601-97-8

Basic information

• Product Name: 3-hydroxyphthalic acid
• Synonyms: 3-hydroxyphthalic acid
• CAS NO: 601-97-8
• Molecular Formula: C₈H₆O₅
• Molecular Weight: 182.13024
• EINECS: 210-011-4
• Mol File: 601-97-8.mol
• Article Data: 11

Chemical Properties

• Melting Point: 161-163 °C
• Boiling Point: 422.5°C at 760 mmHg
• Flash Point: 223.4°C
• Appearance: /
• Density: 1.612g/cm³
• Vapor Pressure: 6.84E-08mmHg at 25°C
• Refractive Index: 1.666
• PKA: 2.67±0.25(Predicted)
• CAS DataBase Reference: 3-hydroxyphthalic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-hydroxyphthalic acid(601-97-8)
• EPA Substance Registry System: 3-hydroxyphthalic acid(601-97-8)

Safety Data

• Hazardous Substances Data: 601-97-8(Hazardous Substances Data)

Usage

Uses

3-Hydroxyphthalic Acid can be used to treat cancer.

Synthesis Reference(s)

Journal of the American Chemical Society, 77, p. 5092, 1955 DOI: 10.1021/ja01624a042

InChI:InChI=1/C8H6O5/c9-5-3-1-2-4(7(10)11)6(5)8(12)13/h1-3,9H,(H,10,11)(H,12,13)

Upstream product

• 830-81-9 1-naphthyl acetate 
• 24736-82-1 diethyl 3-hydroxyphthalate 
• 5434-20-8 3-aminophthalic acid 
• 7664-93-9 sulfuric acid 
• 623-11-0 1-methyl-4-nitrosobenzene 
• 481-42-5 5-hydroxy-2-methyl-1,4-naphthoquinone 
• 7722-84-1 dihydrogen peroxide 
• 2944-49-2 2,3-dimethylanisole 
• 6295-74-5 sulfuric acid mono-[1]naphthyl ester; potassium-salt 
• 15910-11-9 1,4-diacetoxy 1,3-butadiene 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 14963-97-4 3-methoxyphthalic acid 
• 481-39-0 5-hydroxynaphtho-1,4-quinone 
• 117-21-5 3-chlorophthalic anhydride 

Downstream Products

• 37418-88-5 3-hydroxyphthalic anhydride 
• 101976-15-2 3-acetoxyphthalic anhydride 
• 928776-63-0 4-benzyloxy-2-(1-benzyloxy-2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 
• 63382-37-6 4-(benzyloxy)isobenzofuran-1,3-dione 
• 94464-26-3 4-(benzyloxy)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 
• 36669-02-0 2,3-bis(methoxycarbonyl)phenol 
• 1061605-21-7 2-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]oxy}acetic acid 
• 123732-28-5 3-benzyloxy-phthalic acid dimethyl ester 
• 92497-14-8 3-(benzyloxy)phthalic acid 
• 1061604-57-6 2-(2,6-dioxo-piperidin-3-yl)-4-(4-methanesulfonyl-benzyloxy)-isoindole-1,3-dione 
• 1061604-50-9 4-(3,5-dichloro-benzyloxy)-2-(2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione 
• 1061604-83-8 2-(2,6-dioxo-piperidin-3-yl)-4-(4-methoxy-benzyloxy)-isoindole-1,3-dione 
• 1061604-45-2 4-(4-chloro-benzyloxy)-2-(2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione 
• 1061604-60-1 2-(2,6-dioxo-piperidin-3-yl)-4-(3-methoxy-benzyloxy)-isoindole-1,3-dione 

Relevant articles and documents

Method for synthesizing herbicide pyriminobac-methyl in paddy field

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Preparation method of 3-hydroxyl phthalic anhydride

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Practical synthesis of a phthalimide-based Cereblon ligand to enable PROTAC development

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