36698-08-5

Basic information

• Product Name: 1-(2-Benzoyloxyethyl)-5-nitro-2-imidazole-α-phenylethenol benzoate
• CAS NO: 36698-08-5
• Molecular Weight: 483.48
• Mol File: 36698-08-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(2-Benzoyloxyethyl)-5-nitro-2-imidazole-α-phenylethenol benzoate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-Benzoyloxyethyl)-5-nitro-2-imidazole-α-phenylethenol benzoate(36698-08-5)
• EPA Substance Registry System: 1-(2-Benzoyloxyethyl)-5-nitro-2-imidazole-α-phenylethenol benzoate(36698-08-5)

Safety Data

• Hazardous Substances Data: 36698-08-5(Hazardous Substances Data)

Upstream product

• 98-88-4 benzoyl chloride 
• 443-48-1 metronidazole 

Relevant articles and documents

Aroylation of Metronidazole: Synthesis of Imidazo-1,4-oxazepines

Reaction of metronidazole (I) with benzoyl chloride, p-nitrobenzoyl chloride, p-chlorobenzoyl chloride and 2-thenoyl chloride yields the corresponding 2-enol benzoates (e.g.II).Hydrolysis with ethanolic hydrochloric acid yields the expected ketones (IV) while hydrolysis with 1:1 sulphuric acid gives derivatives of the novel imidazo-1,4-oxazepine ring system (e.g.VI).