367-05-5

Upstream product

• 367-12-4 2-fluorophenol 

Downstream Products

• 80071-53-0 6-o-fluorophenoxy-4-thia-1-hexene 
• 574747-39-0 N-benzyl-4-(2-fluorophenoxymethyl)-4-hydroxypiperidine 
• 574747-40-3 spiro[(2,3-dihydro-1,4-benzodioxine)-2,4'-(N-benzylperidine)] 
• 86308-34-1 [2-(2-Fluoro-phenoxy)-phenyl]-acetic acid 
• 86308-49-8 [2-(2-Fluoro-phenoxy)-5-methyl-phenyl]-acetic acid 
• 86308-48-7 [5-Chloro-2-(2-fluoro-phenoxy)-phenyl]-acetic acid 
• 139305-38-7 (E)-1-(4-Fluoro-6,11-dihydrodibenzoxepin-11-yl)-4-(3-phenyl-2-propenyl)piperazine 
• 1273986-54-1 4?chloro?2?(2?fluorophenyloxy)benzoic acid 
• 1580001-22-4 5-(4-chloro-2-(2-fluorophenoxy)benzyl)-3-ethylthio-4H-1,2,4-triazole 
• 1580001-23-5 5-(4-chloro-2-(2-fluorophenoxy)benzyl)-3-propylthio-4H-1,2,4-triazole 
• 1580001-24-6 5-(4-chloro-2-(2-fluorophenoxy)benzyl)-3-benzylthio-4H-1,2,4-triazole 
• 1580001-26-8 ethyl 2-(4-chloro-2-(2-fluorophenoxy)phenyl)acetate 
• 1580001-28-0 2-(4-chloro-2-(2-fluorophenoxy)phenyl)acetic acid hydrazide 
• 1580001-31-5 2-amino-5-(4-chloro-2-(2-fluorophenoxybenzyl))-1,3,4-oxadiazole 

Relevant academic research and scientific papers

Selective ortho-hydroxylation-defluorination of 2-fluorophenolates with a Bis(μ-oxo)dicopper(III) species

The bis(μ-oxo)dicopper(III) species [CuIII 2(μ-O)2(m-XYLMeAN)]2+ (1) promotes the electrophilic ortho-hydroxylation-defluorination of 2-fluorophenolates to give the corresponding catechols, a reaction that is not accomplishable with a (η2:η2-O2) dicopper(II) complex. Isotopic labeling studies show that the incoming oxygen atom originates from the bis(μ-oxo) unit. Ortho-hydroxylation-defluorination occurs selectively in intramolecular competition with other ortho-substituents such as chlorine or bromine. O in, F out: [CuIII2(μ-O) 2(m-XYLMeAN)]2+ is a bis(μ-oxo)dicopper(III) species and promotes the electrophilic ortho-hydroxylation-defluorination of 2-fluorophenolates to give the corresponding catechols. Isotopic labeling shows that the incoming oxygen atom originates from the bis(μ-oxo) unit. Ortho-hydroxylation-defluorination occurs selectively in intramolecular competition with other ortho-substituents such as chlorine or bromine.