36740-09-7 Usage
Description
Morpholin-4-yl(pyridin-3-yl)acetonitrile is a heterocyclic chemical compound characterized by the molecular formula C11H11N3O. It features a morpholine ring and a pyridine ring, along with a nitrile group. morpholin-4-yl(pyridin-3-yl)acetonitrile is recognized for its unique structure and reactivity, which makes it a valuable intermediate in the synthesis of a variety of pharmaceuticals and biologically active compounds. Due to its potential flammability and toxicity, it is crucial to handle this compound with care and in accordance with proper safety protocols.
Uses
Used in Organic Synthesis:
Morpholin-4-yl(pyridin-3-yl)acetonitrile serves as a building block in organic synthesis, contributing to the creation of a wide range of chemical products. Its presence in the synthesis process is instrumental in forming complex organic molecules with specific properties and applications.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, morpholin-4-yl(pyridin-3-yl)acetonitrile is utilized as a key intermediate for the synthesis of pharmaceuticals. Its unique structure allows for the development of compounds with potential therapeutic effects, making it an important component in the discovery and production of new drugs.
Used in Pharmaceutical Production:
Morpholin-4-yl(pyridin-3-yl)acetonitrile is employed in the production of diverse pharmaceuticals, where its reactivity and structural features are leveraged to create biologically active compounds. morpholin-4-yl(pyridin-3-yl)acetonitrile plays a significant role in the advancement of medicinal treatments and the improvement of existing pharmaceutical formulations.
Used in Research and Development:
In research and development settings, morpholin-4-yl(pyridin-3-yl)acetonitrile is used to explore new chemical reactions and pathways, as well as to develop novel compounds with specific biological activities. Its versatility in chemical reactions makes it a valuable tool for scientists working on the frontier of chemical and pharmaceutical innovation.
Used in Chemical Product Development:
Morpholin-4-yl(pyridin-3-yl)acetonitrile is also used in the development of various chemical products beyond the pharmaceutical industry. Its unique properties can be harnessed to create new materials, catalysts, and other specialty chemicals that can be applied in different industries, such as agriculture, materials science, and environmental technology.
Check Digit Verification of cas no
The CAS Registry Mumber 36740-09-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,7,4 and 0 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 36740-09:
(7*3)+(6*6)+(5*7)+(4*4)+(3*0)+(2*0)+(1*9)=117
117 % 10 = 7
So 36740-09-7 is a valid CAS Registry Number.
InChI:InChI=1/C11H13N3O/c12-8-11(10-2-1-3-13-9-10)14-4-6-15-7-5-14/h1-3,9,11H,4-7H2
36740-09-7Relevant articles and documents
A catalytic, one-pot and green synthesis of a-amino nitriles: Cu(BF4)2.x H2O an efficient catalyst
Tadiparthi, Krishnaji,Raghavendra,Kamal, Ahmed
supporting information, p. 440 - 445 (2017/07/24)
The Strecker reaction is a first reported multicomponent reaction for the preparation of a-aminonitriles. The a-aminonitriles are important intermediates for various aminoacids, 1,2-diazines, heterocycles and biologically active compounds like Saframycin A and Ecteinascidin 746. The preparation of a-aminonitriles by Strecker approach using MCR attracted many research groups owing atom economy to avoid multistep synthesis and to follow Green chemistry principles. Methods: A-aminonitriles have been synthesized using Strecker reaction by treatment of aldehydes, amines, with TMSCN in the presence of Cu(BF4)2.xH2O as a catalyst in one pot under neat conditions. Various aromatic and aliphatic aldehydes have been studied with different primary and secondary amines. Results: The reaction condition has been optimized by choosing a model reaction under various solvents and found good yields under neat conditions. Moreover, various catalytic amounts of Cu(BF4)2.xH2O has also been studied and found 3 mole% providing better yields. The reaction has been studied with different substrates of aldehydes and amines. Some of the products were characterized by comparison of their spectral data (1H NMR, 13C NMR, IR and MS) and physical properties with those of authentic samples reported in the literature. Conclusion: Afacile and efficient one-pot synthesis of a-amino nitriles at ambient temperature using copper(II)tetrafluoroborate as a novel catalyst under solvent-free conditions via Strecker reaction is reported. The process is simple and environmentally benign using the commercially available and inexpensive catalyst.
