36768-52-2

Upstream product

• 104236-76-2 5'-chloro-2'-hydroxy-3.4-dimethoxy-trans-chalcone 
• 116194-66-2 6-chloro-2-(3,4-dimethoxy-phenyl)-chroman-4-ol 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 1450-74-4 5-chloro-2-hydroxyacetophenone 
• 26028-34-2 5’-chloro-2’-hydroxy-3,4-dimethoxychalcone 
• 39856-08-1 3,4-dimethoxy-cinnamoyl chloride 
• 106-48-9 4-chloro-phenol 
• 1376543-61-1 C₁₈H₁₇ClO₅ 
• 27007-53-0 methyl-2-bromo-5-chlorobenzoate 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 1301225-18-2 C₁₇H₁₄BrClO₄ 
• 7446-08-4 selenium(IV) oxide 
• 123-51-3 i-Amyl alcohol 
• 116194-65-1 6-Chloro-2-(4-methoxy-phenyl)-chroman-4-ol 

Relevant academic research and scientific papers

A novel one-pot synthesis of flavones

In this paper, a one-pot facile route for the BiCl3/RuCl3-mediated synthesis of functionalized flavones is described, including: (i) intermolecularortho-acylation of substituted phenols with cinnamoyl chlorides, and (ii) intramolecular cyclodehydrogenation of the resultingo-hydroxychalcones. The reaction conditions are discussed herein.

K2CO3-catalyzed synthesis of chromones and 4-quinolones through the cleavage of aromatic C-O bonds

Phenol-derived electrophiles are favorable substrates because phenols are naturally abundant or can be readily prepared from other aromatic compounds. However, the cleavage of aromatic C-O bonds is a great challenge because of their high energy. K2CO3-catalyzed intramolecular cyclization of 1-(2-alkoxyphenyl)-3-akylpropane-1,3-dione and 3-(alkylimino)-1-(2-methoxyphenyl)-2-methylpropan-1-one derivatives via the selective cleavage of aromatic C-O bonds is reported. The corresponding chromone and 4-quinolone derivatives were obtained in reasonable yields.

Transition-metal-free intramolecular Ullmann-type O-arylation: Synthesis of chromone derivatives

(Chemical Equation Presented) Expect the upexpected: A transition-metal- free approach to access chromone derivatives has been developed. The intramolecular O-arylation of substituted 1-(2-haloaryl)-propane-1,3-diones in DMF in the presence of K2CO3 gave the corresponding target products in good to excellent yields (see scheme; DMF = N,N′- dimethylformamide).

Synthesis of chromones and pyrazolines as antimicrobial & antifungal agents

A series of chromones and pyrazolines have been synthesized and evaluated for their antimicrobial and antifungal activity against Gram+ve and Gram-ve microorganisms. 2-Hydroxy acetophenone on treatment with substituted aldehydes gave the corresponding cha

Dimethylsulfoxide-iodine catalysed deprotection of 2′- allyloxychalcones: Synthesis of flavones

A new one-pot method is described for the removal of O-allyl protecting groups under oxidative conditions at neutral pH. 2′-Allyloxychalcones undergo deprotection and subsequent oxidative cyclisation to give flavones. The general applicability of the reagent has been studied.

DDQ Oxidation of Flavan-4-ols - A New Method for Synthesis of Flavones

Flavan-4-ols on oxidation with two mol of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ) in benzene afford flavones as the major products and flavanones as the minor products.