3678-65-7

Usage

Synthesis Reference(s)

The Journal of Organic Chemistry, 50, p. 4410, 1985 DOI: 10.1021/jo00222a050

InChI:InChI=1/C7H8ClN/c1-2-7-5-6(8)3-4-9-7/h3-5H,2H2,1H3

Upstream product

• 50826-64-7 4-amino-2-ethylpyridine 
• 3678-63-5 4-chIoro-2-methylpyridine 
• 74-88-4 methyl iodide 
• 38594-62-6 2-ethyl-4-nitropyridine N-oxide 
• 4833-24-3 2-ethylpyridine 1-oxide 
• 626-61-9 4-Chloropyridine 
• 98420-85-0 4-Chloro-2-ethyl-2H-pyridine-1-carboxylic acid phenyl ester 

Downstream Products

• 850250-63-4 {4-[(2-ethylpyridin-4-yl)oxy]phenyl}amine 
• 910215-45-1 C₁₄H₁₆N₂O 

Relevant academic research and scientific papers

AZETIDINES AND CYCLOBUTANES AS HISTAMINE H3 RECEPTOR ANTAGONISTS

The invention relates to compounds of formula (I) wherein R, R0, R1, m, n and X1 to X4 have the meaning as cited in the description and the claims. Said compounds are useful as Histamine H3 receptor antagonists. The invention also relates to pharmaceutical compositions, the preparation of such compounds as well as the production and use as medicament.

PYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS

Pyrimidine derivatives of formula (I), pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are disclosed and claimed.

PYRIMIDINE DERIVATIVES FOR TREATMENT OF HYPERPROLIFERATIVE DISORDERS

Pyrimidine derivatives of formula (I) in which J and Y represent aromatic or heteroaromatic rings; R2, G, G', and G" represent substituent groups and R2a represents H or halogen; L represents a linking group; and M represents CH or N. Pharmaceutical compositions containing these compounds, and methods of using these compounds in treatment of hyperproliferative diseases such as cancer are also disclosed and claimed.