36810-78-3Relevant academic research and scientific papers
A photoredox catalyzed radical-radical coupling reaction: Facile access to multi-substituted nitrogen heterocycles
Li, Weipeng,Duan, Yingqian,Zhang, Muliang,Cheng, Jian,Zhu, Chengjian
supporting information, p. 7596 - 7599 (2016/07/06)
Visible light induced photoredox catalysis is an efficient method for radical activation. Herein, we report the photoredox catalysis involving an intramolecular radical-radical coupling reaction that proceeds through a biradical intermediate. This protocol represents a new synthetic route to construct multi-substituted N-heterocycles. Four, five and six-membered N-heterocyclic structures with a quaternary carbon center are accessible under mild conditions.
Synthesis of α-Keto Amides by a Pyrrolidine/TEMPO-Mediated Oxidation of α-Keto Amines
Yu, Lu,Somfai, Peter
supporting information, p. 2587 - 2590 (2016/11/11)
A mild procedure has been developed for the synthesis of α-keto amides by α-oxidation of the corresponding α-keto amines mediated by pyrrolidine and TEMPO. The method can also be applied to the synthesis of α-keto thioamides and α-keto amidines.
