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3682-04-0

Naringenin triacetate is a chemical compound derived from naringenin, a flavonoid present in citrus fruits. It is a modified form of naringenin with three acetyl groups attached to its hydroxyl groups, enhancing its solubility and stability. Naringenin triacetate has garnered attention for its potential pharmaceutical applications, particularly due to its anti-inflammatory, antioxidant, and anti-cancer properties. Preclinical studies have demonstrated its efficacy in inhibiting cancer cell growth and reducing inflammation, positioning naringenin triacetate as a promising candidate for therapeutic and pharmaceutical uses.

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  • 3682-04-0 Structure

  • Basic information

    1. Product Name: Naringenin triacetate
    2. Synonyms: Naringenin triacetate;2-(4-Acetoxyphenyl)-4-oxochroMan-5,7-diyl diacetate
    3. CAS NO:3682-04-0
    4. Molecular Formula: C21H18O8
    5. Molecular Weight: 398
    6. EINECS: 200-258-5
    7. Product Categories: N/A
    8. Mol File: 3682-04-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Naringenin triacetate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Naringenin triacetate(3682-04-0)
    11. EPA Substance Registry System: Naringenin triacetate(3682-04-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 3682-04-0(Hazardous Substances Data)

3682-04-0 Usage

Uses

Used in Pharmaceutical Applications:
Naringenin triacetate is used as a pharmaceutical agent for its anti-inflammatory, antioxidant, and anti-cancer properties. It has shown the ability to inhibit the growth of cancer cells and reduce inflammation, making it a potential candidate for the development of new therapeutics.
Used in Anticancer Applications:
In the field of oncology, naringenin triacetate is used as an anticancer agent. Its potential to inhibit the growth of various types of cancer cells has been demonstrated in preclinical studies, suggesting its utility in the treatment of cancer.
Used in Drug Delivery Systems:
Naringenin triacetate is also investigated for its potential use in drug delivery systems. Its improved solubility and stability compared to naringenin make it a suitable candidate for enhancing the delivery, bioavailability, and therapeutic outcomes of associated pharmaceuticals. This application can lead to the development of more effective drug formulations and targeted therapies.

Check Digit Verification of cas no

The CAS Registry Mumber 3682-04-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,6,8 and 2 respectively; the second part has 2 digits, 0 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 3682-04:
(6*3)+(5*6)+(4*8)+(3*2)+(2*0)+(1*4)=90
90 % 10 = 0
So 3682-04-0 is a valid CAS Registry Number.

3682-04-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name Naringenin triacetate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3682-04-0 SDS

3682-04-0Relevant articles and documents

Peracetylation of polyphenols under rapid and mild reaction conditions

Castro, Rosane Nora,Freire de Lima, Marco Edilson,Pitasse-Santos, Paulo,de Alcantara Pinto, Douglas Chaves,de Souza, Gabriela Alves

supporting information, (2022/01/31)

Structural modifications are an important tool for studying the properties of naturally occurring polyphenols. Regarding the preparation of acetyl esters, the presence of hydroxyl groups stabilized by intramolecular hydrogen bonds may pose an obstacle for

ACYLATED ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF AUTOIMMUNE DISORDERS

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Page/Page column 135, (2019/12/28)

Disclosed herein are acylated active agents (e.g., acylated catechin polyphenols, acylated carotenoids, acylated mesalamines, acylated sugars, acylated shikimic acids, acylated ellagic acid, acylated ellagic acid analogue, and acylated hydroxybenzoic acids), active agent combinations (e.g., with a second agent that is a fatty acid) and methods of their use, e.g., for modulating an autoimmunity marker or for treating an autoimmune disorder.

ACTIVE AGENTS AND METHODS OF THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS AND NONALCOHOLIC FATTY LIVER DISEASE

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Page/Page column 67; 76, (2019/12/28)

Disclosed herein are active agents, compositions containing them, unit dosage forms containing them, and methods of their use, e.g., for treating a metabolic disorder or nonalcoholic fatty liver disease or for modulating a metabolic marker or nonalcoholic fatty liver disease marker.

An efficient method for C8-prenylation of flavonols and flavanones

Kawamura, Tomoyuki,Hayashi, Moemi,Mukai, Rie,Terao, Junji,Nemoto, Hisao

scheme or table, p. 1308 - 1314 (2012/06/30)

Synthesis of C8-prenylated flavonols and flavanones via the palladium-catalyzed 7-O-1,1-dimethylprop-2-enylation, followed by Claisen rearrangement is described. Two regioselectivities (carbon-carbon bond formation at either the tail or head of the prenyl

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